Results 71 to 80 of about 125,120,791 (279)
Review of Life Cycle Assessment in Agro-Chemical Processes [PDF]
, 2010 Life Cycle Assessment (LCA) is a method used to evaluate the potential impacts on the environment of a product, process, or activity throughout its life cycle.
Sayed Tamizuddin Gillani +12 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Multi-Objective Optimization in Chemical Engineering: Developments and Applications
, 2013 10.1002/9781118341704Multi-Objective Optimization in Chemical Engineering: Developments and Applications1 ...
Rangaiah, G.P., Bonilla-Petriciolet, A.
core +1 more source
E-newsletter school of civil engineering: staff at SCE-structural and material engineering (StrucM) [PDF]
, 2023 The Structural and Material Engineering (StrucM) team at the School of Civil Engineering comprises dedicated academics and researchers with expertise in structural analysis, construction materials, structural design, concrete technology, steel and ...
UiTM, College of Engineering
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 1996 This present volume contains the text of all contributions (oral and posters), except for the four invited papers, which were presented at the 3rd International Symposium on High Pressure Chemical Engineering on October 7-9, 1996.
Trepp, Ch. +2 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Journal of Biological EngineeringNatural polysaccharides are versatile building blocks for regenerative biomaterials because of their structural diversity, generally favorable biocompatibility and biodegradability, chemical tunability, and capacity for biologically relevant interactions.
Sameh S. Ali +7 more
doaj +1 more source