Results 91 to 100 of about 125,120,791 (279)
Biomaterial‐Based Metabolic Regulation in Regenerative Engineering
Recent advances in cell metabolism studies have deepened the appreciation of the role of metabolic regulation in influencing cell behavior during differentiation, angiogenesis, and immune response in the regenerative engineering scenarios.
Chuying Ma +3 more
doaj +1 more source
BULLETIN OF CHEMICAL REACTION ENGINEERING & CATALYSIS (ISSN 1978-2993), Volume 7, Number 2, Year 2012 is an electronic international journal. The journal is a media for communicating all research activities in chemical reaction engineering and ...
Istadi Istadi
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Horizons in Chemical Engineering [PDF]
Looking back over the last five decades the development of modern Chemical Engineering is traced. Some of the more important milestones in the development are pointed out and it is noted that Professor August Guyer has been actively engaged in Chemical ...
Weber, Harold C.
core +1 more source
Aluminum is the most used non-ferrous metal, with a well-established recycling procedure, but this process also produces new residues. We recently proposed an integrated laboratory practice based on the recovery of aluminum from the slag generated during
Alejandro Jiménez +3 more
doaj +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Design Guidelines and Manufacturing Methods for Microreaction Devices
Microreaction technology is a powerful tool for the evaluation of new reaction pathways, process intensification in chemical engineering and combinatorial material development.
Wolfgang Ehrfeld
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The chemical industry plays a crucial role in strengthening the manufacturing sector of China, and chemical industrial parks are key platforms for new industrialization.
Chen Lyujun +3 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

