Results 101 to 110 of about 349,954 (287)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cost analyses of chemical micro processing for highly intensified and high-value raw material processes: real business and virtual cases

, 2006
As a result of its rapid development within the last years an increasing commercial interest on micro process engineering is given. Process intensification effects of this novel technology were clearly demonstrated.
Löwe, Holger, Krtschil, Ulrich, Löb, Patrick, Hessel, Volker, Kralisch, Dana, Kreisel, Guenter, Küpper, Michael, Schenk, Rainer   +7 more
core  

Evaluation of the Possibility for Using Polypropylene/Graphene Composite as Bipolar Plate Material Instead of Polypropylene/Graphite Composite [PDF]

, 2016
To reduce the bipolar plate weight and keep the desired power density of a low temperature fuel cell, thermoplastic composite bipolar plates have been fabricated for low temperature fuel cell applications.
Fowler, Michael; Department of Chemical Engineering, Faculty of Engineering, University of Waterloo, Ontario, Canada, Seok Jun, Yun; Department of Chemical Engineering, Faculty of Engineering, University of Waterloo, Ontario, Canada, Yu, Aiping; Department of Chemical Engineering, Faculty of Engineering, University of Waterloo, Ontario, Canada, Onyu, Kannika; Department of Industrial Chemistry, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok, Bangkok, Thailand, Prapainainar, Chaiwat; Department of Chemical Engineering, Faculty of Engineering, King Mongkut’s University of Technology North Bangkok, Bangkok, Thailand, Prissanaroon-Ouajai, Walaiporn; Department of Industrial Chemistry, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok, Bangkok, Yeetsorn, Rungsima; Department of Industrial Chemistry, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok, Bangkok, Thailand   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Fabrication and characterisation of 3 dimensional scaffold for tissue engineering application via microstereolithography technique [PDF]

Microstereolithography is a method used for rapid prototyping of polymeric and ceramic components. This technique converts a computer-aided design (CAD) to a three dimensional (3D) model, and enables layer-per-layer fabrication curing a liquid resin ...
Talib, Marina
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Template- and Magnetic Field-Free Chemical Reduction of Ni Nanochains for Ni–Al2O3 Cermet Films: Growth Control, Characterization, and Application

ACS Omega, 2020
Tanyakorn Muangnapoh, Piyarach Srimara, Paravee Vas-Umnuay   +2 more
doaj   +1 more source

Development of 2nd Generation Proteinous Bioplastics

, 2009
Current environmental and economic concerns surrounding the use of petroleum-based plastics, has led to increased study of renewable natural polymers, such as proteins.
van den Berg, Lisa E.
core  

Simulation And Techno-economic Evaluation Of Large Scale 2.5-dimethylfuran Production From Fructose

, 2015
Conceptual process synthesis (CPS) is an important issue in chemical processing industries. This paper is based on a schematic diagram of 2.5 dimethylfuran (DMF) production from fructose [ Y. R. Leshkov, C. J. Barrett, Z. L. Liu, J. A.
Rodrigues F.A., Guirardello R.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source