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Chemical penetration enhancers: a patent review
Expert Opinion on Therapeutic Patents, 2009Ever since transdermal drug delivery came into existence, it has offered great promises, although most of them are yet to be fulfilled owing to some intrinsic restrictions of the transdermal route. On the positive side, transdermal drug delivery systems present advantages including non-invasiveness, prolonged therapeutic effect, reduced side effects ...
Abdul, Ahad +6 more
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On the chemical enhancement in SERS
AIP Conference Proceedings, 2012In Surface-enhanced Raman scattering (SERS), the Raman signal of a molecule adsorbed on a metal surface is enhanced by many orders of magnitude. This provides a "finger-print" of molecules which can be used in ultrasensitive sensing devises. Here we present a time-dependent density functional theory (TDDFT) study of the molecule-surface chemical ...
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Interfacial chemical reactivity enhancement
The Journal of Chemical PhysicsInterfacial enhancements of chemical reaction equilibria and rates in liquid droplets are predicted using a combined theoretical and experimental analysis strategy. Self-consistent solutions of reaction and adsorption equilibria indicate that interfacial reactivity enhancement is driven primarily by the adsorption free energy of the product (or ...
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Enhancement of the chemical stability in confined δ-Bi2O3
Nature Materials, 2015Bismuth-oxide-based materials are the building blocks for modern ferroelectrics, multiferroics, gas sensors, light photocatalysts and fuel cells. Although the cubic fluorite δ-phase of bismuth oxide (δ-Bi2O3) exhibits the highest conductivity of known solid-state oxygen ion conductors, its instability prevents use at low temperature.
Sanna, Simone +9 more
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Combining Chemical Permeation Enhancers for Synergistic Effects
European Journal of Drug Metabolism and Pharmacokinetics, 2015Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study investigated binary combinations of chemical drug absorption enhancers to determine if synergistic drug absorption enhancement effects exist ...
Trizel du Toit +6 more
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Enhancement of Sludge Settling with Chemical Additives
Water Environment Research, 2009Solids in aeration tank effluents contribute to the total organic content and suspended solids concentration, and violates disposal and reuse standards. Therefore, improving the settling properties of sludge helps produce an effluent with a quality that conforms to effluent standards, assuming all other conditions for good settling in the sedimentation
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Chemical Flooding for Enhanced Recovery
Energy Sources, Part A: Recovery, Utilization, and Environmental Effects, 2012Abstract Chemical flooding is an important enhancing recovery technology. Displacement mechanisms of different displacement agents were dissimilar. There were some experiments finished to research the effect of chemical flooding. After evaluation of displacement systems, recoveries of all formulas were determined and the recovery contour diagram was ...
Q. Yu +4 more
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Chemical penetration enhancers.
International journal of pharmaceutical compounding, 2014Chemical penetration enhancers are utilized in topical preparations as a method for enhancing permeation of drugs across the skin. In particular, they are utilized for transdermal delivery of medications in an attempt to produce a systemic response, to avoid first-pass metabolism, and to decrease the gastrointestinal transit time observed with oral ...
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2020
It is often a challenge to effectively deliver drugs through the skin into the internal environment. Compared with oral administration and other dosage forms, transdermal administration has multiple advantages. Among the various transdermal administration approaches, microneedles emerge as a powerful tool in recent years, owing to its simple concept ...
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It is often a challenge to effectively deliver drugs through the skin into the internal environment. Compared with oral administration and other dosage forms, transdermal administration has multiple advantages. Among the various transdermal administration approaches, microneedles emerge as a powerful tool in recent years, owing to its simple concept ...
openaire +1 more source