Results 1 to 10 of about 77,170 (289)

Host–Guest Complexation of Olmesartan Medoxomil by Heptakis(2,6-di-O-methyl)-β-cyclodextrin: Compatibility Study with Excipients

Pharmaceutics
Background: Olmesartan medoxomil (OLM) is the prodrug of olmesartan, an angiotensin II type 1 receptor blocker that has antihypertensive and antioxidant activities and renal protective properties.
Dana Emilia Man, Ema-Teodora Nițu, Claudia Temereancă, Laura Sbârcea, Adriana Ledeți, Denisa Ivan, Amalia Ridichie, Minodora Andor, Alex-Robert Jîjie, Paul Barvinschi, Gerlinde Rusu, Renata-Maria Văruţ, Ionuț Ledeți   +12 more
doaj   +1 more source

Optimization of Preparation Processing and Evaluation of Anticoagulant Activity in Vitro of Astragalus Composite Granular Tea

Shipin gongye ke-ji
In this study, Astragalus composite granular tea was prepared by decocting, concentrating, granulation and drying processes of the twelve kinds of dietary Chinese herbs such as Astragalus, Salvia miltiorrhiza and Panax notoginseng.
Lixia WANG, Xiuqing ZHANG, Mengchen FAN, Jingjing WU, Menglong CHEN, Zhenguo MA, Pei LIU   +6 more
doaj   +1 more source

Lipids in pharmaceutical and cosmetic preparations

Grasas y Aceites, 2000
In this paper, a review of the applications of lipids in the pharmaceutical field has been reported. In a first stage, different lipids used as excipients in cosmetics and medicines have been described.
Antonio M. Rabasco Alvarez, María Luisa González Rodríguez   +1 more
doaj   +1 more source

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

Frontiers in Pharmacology
Drug-related acute pancreatitis (AP), acute interstitial nephritis (AIN) and drug-induced liver injury (DILI) are rare but serious adverse drug reactions (ADRs) that can have life-threatening consequences.
Olga Rogozina, Carmen Ruiz-Fernández, Susana Martín-López, Ibtissam Akatbach-Bousaid, Miguel González-Muñoz, Elena Ramírez   +5 more
doaj   +1 more source

DSC, TGA-FTIR and FTIR Assisted by Chemometric Factor Analysis and PXRD in Assessing the Incompatibility of the Antiviral Drug Arbidol Hydrochloride with Pharmaceutical Excipients

Molecules
Arbidol hydrochloride is an antiviral product widely used in Russia and China for the treatment of, among other diseases, influenza. In recent years, it has turned out to be highly effective against COVID-19.
Barbara Rojek, Agata Bartyzel, Wiesław Sawicki, Alina Plenis   +3 more
doaj   +1 more source

A Thermal-Analysis-Technique-Based Mechanistic Approach toward the Release of Omeprazole from Solid Dosage Forms

Scientia Pharmaceutica
The design, development, and release kinetics of omeprazole (OME) from solid dosage forms have been investigated. These formulations were examined for their resilience in pH = 4.5 buffer solutions and their rate of disintegration in a small-intestine ...
Georgios Agapakis, Angeliki Siamidi, Stefanos Kikionis, Marilena Vlachou, Natassa Pippa   +4 more
doaj   +1 more source

Impact of Polyvinylpyrrolidone-Vinyl Acetate Copolymer and Sodium Starch Glycolate Excipients on Phenolic Extraction from Red Clover: Enhancing Biological Activity and Antioxidant Potential

Pharmaceutics
Adding certain excipients during the extraction process can enhance the concentration of target compounds, leading to potentially increased biological properties of the plant extract.
Jurga Andreja Kazlauskaite, Mindaugas Marksa, Jurga Bernatoniene   +2 more
doaj   +1 more source

EXCIPIENTS IN ORAL SUSPENSIONS

Разработка и регистрация лекарственных средств, 2019
The article describes the approaches to classification and separation of groups of excipients in oral suspensions of both domestic and foreign authors. A number of existing classifications of excipients for oral suspensions are presented. The analysis of
V. V. Vernikovsky, E. V. Tretyakova
doaj  

THE ANALYSIS OF THE PHARMACEUTICAL MARKET ON THE EXAMPLE OF MEDICINES OF GROUP OF INHIBITORS OF THE PROTON POMP

Разработка и регистрация лекарственных средств, 2019
In this research is carried out the review of the Russian pharmaceutical market and the comparative characteristic of medicines of group of inhibitors of a proton pomp.
N. V. Mazova, A. L. Marchenko, N. V. Marchenko   +2 more
doaj  

Edaravone for the Treatment of Motor Neurone Disease: A Critical Review of Approved and Alternative Formulations against a Proposed Quality Target Product Profile

Pharmaceutics
Edaravone is one of two main drugs for treating motor neurone disease (MND). This review proposes a specific quality target product profile (QTPP) for edaravone following an appraisal of the issues accounting for the poor clinical uptake of the approved ...
Riuna O’Neill, Okhee Yoo, Philip Burcham, Lee Yong Lim   +3 more
doaj   +1 more source