Results 61 to 70 of about 6,392,950 (289)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Fishworks shop

open access: yes, 2006
Covers OCLC #38937785, OCLC #1100114907"News from Oregon's Fish Restoration and Enhancement Program and Salmon Trout Enhancement Program."Title from captionErrors in numbering: v. 3, no. 1, spring 1998, called v. 2, no. 1; v. 3, no.

core  

Phase Distribution of Gas–Liquid Slug–Annular Flow in Horizontal Parallel Micro-Channels

open access: yesEnergies
As a transitional flow pattern, slug–annular flow occurs over a wide range of operating conditions in micro-channels while its distribution in parallel micro-channels has not been well characterized.
Yanchu Liu   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Genome-Wide Identification and Expression Analysis of the PsTPS Gene Family in Pisum sativum

open access: yesHorticulturae
This study aimed to explore the role of the trehalose-6-phosphate synthase (TPS) gene family in the adaptation of peas to environmental stress. A comprehensive analysis of the PsTPS gene family identified 20 genes with conserved domains and specific ...
Hao Yuan   +9 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Genome-wide identification and expression analysis of the PsKIN gene family in pea

open access: yesFrontiers in Genetics
Peas (Pisum sativum L.) serve as a vital model for plant development and stress research. The kinesin (KIN) gene family, encoding essential motor proteins, remains understudied in peas.
Hao Yuan   +12 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

CHEMICAL ENHANCEMENT OF SUPERCONDUCTIVITY [PDF]

open access: yesProceedings of the National Academy of Sciences, 1965
H M, McConnell   +3 more
openaire   +2 more sources

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