Results 71 to 80 of about 6,392,950 (289)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Antibacterial enhancement of antibiotic activity by Enterolobium contortisiliquum (Vell.) Morong

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To identify the main chemical classes of compounds from aqueous extract of Enterolobium contortisiliquum (E. contortisiliquum) seed bark and to evaluate its antibacterial activity, as well as its potential to increase the activity of ...
Zildene de Sousa Silveira, Nair Silva Macêdo, Thiago Sampaio de Freitas, Ana Raquel Pereira da Silva, Joycy Francely Sampaio dos Santos, Maria Flaviana Bezerra Morais-Braga, José Galberto Martins da Costa, Raimundo Nonato Pereira Teixeira, Jean Paul Kamdem, Henrique Douglas Melo Coutinho, Francisco Assis Bezerra da Cunha   +10 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Surface-Enhanced Raman Scattering Enabled by a Hybrid Microfiber–Plasmonic Structure with Monolayer MoS₂

Photonics
We demonstrate a mechanism-oriented Surface-Enhanced Raman Scattering (SERS) platform based on a hybrid structure integrating monolayer molybdenum disulfide (MoS2) and gold nanospheres (AuNSs) on an optical microfiber (MF).
Xiaodong Zhao, Kaixiang Zhang, Chunlei Yu, Ning Zhou   +3 more
doaj   +1 more source

Dynamics of Photo‐Induced Surface Oxygen Vacancies in Metal‐Oxide Semiconductors Studied Under Ambient Conditions

Advanced Science, 2019
Surface‐enhanced Raman spectroscopy (SERS) is a powerful analytical technique commonly used in the detection of traces of organic molecules. The mechanism of SERS is of a dual nature, with Raman scattering enhancements due to a combination of ...
Daniel Glass, Emiliano Cortés, Sultan Ben‐Jaber, Thomas Brick, William J. Peveler, Christopher S. Blackman, Christopher R. Howle, Raul Quesada‐Cabrera, Ivan P. Parkin, Stefan A. Maier   +9 more
doaj   +1 more source

RNA-Seq analysis reveals transcript diversity and active genes after common cutworm (Spodoptera litura Fabricius) attack in resistant and susceptible wild soybean lines

BMC Genomics, 2019
Background Common cutworm (CCW) is highly responsible for destabilizing soybean productivity. Wild soybean is a resource used by breeders to discover elite defensive genes.
Haiping Du, Xiao Li, Lihua Ning, Rui Qin, Qing Du, Qing Wang, Haina Song, Fang Huang, Hui Wang, Deyue Yu   +9 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification

Nanomaterials, 2019
Progress in the field of biocompatible SERS nanoparticles has promising prospects for biomedical applications. In this work, we have developed a biocompatible Raman probe by combining anisotropic silver nanoparticles with the dye rhodamine 6G followed by
Carlos Caro, Pedro Quaresma, Eulália Pereira, Jaime Franco, Manuel Pernia Leal, Maria Luisa García-Martín, Jose Luis Royo, Jose Maria Oliva-Montero, Patrick Jacques Merkling, Ana Paula Zaderenko, David Pozo, Ricardo Franco   +11 more
doaj   +1 more source

Post-Assay Chemical Enhancement for Highly Sensitive Lateral Flow Immunoassays: A Critical Review. [PDF]

Biosensors (Basel), 2023
Panferov VG, Zherdev AV, Dzantiev BB.
europepmc   +1 more source