Results 111 to 120 of about 6,305,042 (282)

A Comparative Study of Kinetic Reaction Schemes for the Isomerization Process of the C6 Series

open access: yesApplied Sciences
The conversion of n-hexane into its isomers is highly relevant in the petroleum refining industry due to its contribution to improving gasoline quality by increasing the octane number.
Diana K. Díaz-Cervantes   +7 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The Formalism of Chemical Thermodynamics Applied to an Oscillatory Multistep Chemical System

open access: yesIngeniería e Investigación
The thermodynamic optimization of a process focuses on consumption, production, and efficient use of energy. The unsteady-state nature of batch reactor processing requires describing the set of processes’ dynamic behavior for energy optimization.
Jean P. Montoya   +2 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Development of a Three-Tier Chemical Equilibrium Multiple-Choice Test to Assess Higher-Order Thinking Skills Based on Brookhart’s Categories

open access: yesJournal of Educational Chemistry
This study aimed to develop and validate the Three-Tier Chemical Equilibrium Multiple-Choice Test–HOTS (TTCEMCT–HOTS) instrument. The method employed in this study was Research and Development (R&D) based on Brookhart’s (2010) indicators of higher-order ...
Neneng Fauziyah   +2 more
doaj   +1 more source

Language and discourse in conceptual models for chemical equilibrium [PDF]

open access: yesInvestigações em Ensino de Ciências, 2007
A semiotic perspective is used in order to establish the features impressed by language and discourse on particular subject matter content, the chemical equilibrium.
Giovanna Lombardi, Concesa Caballero
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

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