Results 91 to 100 of about 368,451 (291)

CHEMICAL-EQUILIBRIA IN METHANOL SYNTHESIS FROM METHYL FORMATE [PDF]

open access: yes, 1990
The chemical equilibria of the gas-phase methanol production from methyl formate were studied by analyzing the hydrugenolysis reaction (HCOOCH3+ 2H2 -2CH3OH) and decarbonylation reaction (HCOOCH3 CH3OH + CO) occurring concurrently.The equilibrium ...
KIM, Jae Chang   +9 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Manufacture of Industrial Scale Bagasse Biochar: Effect of Temperature And Residence Time And Biochar Characterization [PDF]

open access: yes
. Bagasse is a waste that can still be utilized, one of which is processed into biochar. In this study, bagasse waste came from a sugar factory in Majalengka, Cirebon, West Java.
Hakika, Dhias Cahya   +2 more
core   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Impact parameter dependencies in Pb(160 AGeV)+Pb reactions : hydrodynamical vs. cascade calculations [PDF]

open access: yes, 2005
We investigate the impact parameter dependence of the specific entropy S/A in relativistic heavy ion collisions. Especially the anti-Lambda/anti-proton ratio is found to be a useful tool to distinguish between chemical equilibrium assumptions assumed in ...
Greiner, Walter   +6 more
core  

Machine Learning vs. Real-World Data: Assessing ANN Performance in COD Removal in Animal Feed Processing Wastewater [PDF]

open access: yes
This research established an artificial neural network (ANN) aimed at optimizing ozonation for chemical oxygen demand (COD) reduction in animal feed plant wastewater.
Pertiwi, Beta Cahaya   +3 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Utilization of Tofu Liquid Waste as Liquid Organic Fertilizer Using the Fermentation Method with Activator Effective Microorganisms 4 (EM-4): A Review [PDF]

open access: yes
Liquid organic fertilizer is organic fertilizer in liquid form which is partly or wholly derived from organic compounds such as plant, animal and industrial residues, in solid or liquid form.
Maryudi, Maryudi   +2 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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