Results 81 to 90 of about 368,451 (291)

Some considerations on the fundamentals of chemical kinetics: steady state, quasi-equilibrium, and transition state theory [PDF]

open access: yes, 2019
The elementary reaction sequence A ↔ I → P is the simplest mechanism for which the steady-state and quasi-equilibrium kinetic approximations can be applied.
Pérez de Benito, Joaquín F.
core   +1 more source

Simulação do equilíbrio: o método de Monte Carlo Equilibrium simulation: Monte Carlo method

open access: yesQuímica Nova, 2007
We make several simulations using the Monte Carlo method in order to obtain the chemical equilibrium for several first-order reactions and one second-order reaction. We study several direct, reverse and consecutive reactions.
Alejandro López-Castillo   +1 more
doaj   +1 more source

Understanding Le Châtelier’s principle fundamentals: five key questions

open access: yesChemistry Teacher International, 2021
The well-known Le Châtelier’s principle is almost always mentioned when dealing with chemical equilibrium. Nevertheless, although a must in most general chemistry courses starting from the secondary level, when students face questions about it, some ...
Peris Miguel
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Aerodynamic Design of a Laval Nozzle for Real Gas Using Hodograph Method

open access: yesAerospace, 2018
We propose an approach for the design of the subsonic part of plane and axisymmetric Laval nozzles for real gases. The proposed approach is based on the hodograph method and allows one to solve the inverse design problem directly.
Aleksandr Chikitkin   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

From Steam Engines to Chemical Reactions: Gibbs’ Contribution to the Extension of the Second Law

open access: yesEntropy, 2016
The present work analyzes the foundations of Gibbs’ thermodynamic equilibrium theory, with the general aim of understanding how the Second Law—as formulated by Clausius in 1865—has been embodied into Gibbs’ formal system and extended to processes ...
Emilio Marco Pellegrino   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Characteristic of the CaO-MgO Material Derived from Dolomite via Precipitation-Dehydration Method [PDF]

open access: yes
. This research utilized dolomite rock (CaMg(CO2)2) to produce CaO-MgO material using precipitation-dehydration. The precipitation-dehydration method was carried out by dissolving dolomite in 10% hydrochloric acid (HCl) solvent and precipitating in 2 N ...
Pertiwi, Beta Cahaya   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy