Results 71 to 80 of about 6,305,042 (282)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Machine Learning vs. Real-World Data: Assessing ANN Performance in COD Removal in Animal Feed Processing Wastewater [PDF]

open access: yes
This research established an artificial neural network (ANN) aimed at optimizing ozonation for chemical oxygen demand (COD) reduction in animal feed plant wastewater.
Pertiwi, Beta Cahaya   +3 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Simulação do equilíbrio: o método de Monte Carlo Equilibrium simulation: Monte Carlo method

open access: yesQuímica Nova, 2007
We make several simulations using the Monte Carlo method in order to obtain the chemical equilibrium for several first-order reactions and one second-order reaction. We study several direct, reverse and consecutive reactions.
Alejandro López-Castillo   +1 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Aerodynamic Design of a Laval Nozzle for Real Gas Using Hodograph Method

open access: yesAerospace, 2018
We propose an approach for the design of the subsonic part of plane and axisymmetric Laval nozzles for real gases. The proposed approach is based on the hodograph method and allows one to solve the inverse design problem directly.
Aleksandr Chikitkin   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Think-Pair-Square: A Collaborative Approach to Enhancing Critical Thinking Skills in Chemical Equilibrium

open access: yesJournal of Educational Chemistry
Low levels of critical thinking skills among students on the topic of chemical equilibrium pose a significant challenge in chemistry education. This topic demands strong analytical, evaluative, and problem-solving abilities.
Hilga Natasya Sinaga   +2 more
doaj   +1 more source

From Steam Engines to Chemical Reactions: Gibbs’ Contribution to the Extension of the Second Law

open access: yesEntropy, 2016
The present work analyzes the foundations of Gibbs’ thermodynamic equilibrium theory, with the general aim of understanding how the Second Law—as formulated by Clausius in 1865—has been embodied into Gibbs’ formal system and extended to processes ...
Emilio Marco Pellegrino   +2 more
doaj   +1 more source

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