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This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
The (r)evolution of chemical space and molecular modeling: a time-resolved perspective. [PDF]
Del Moral-Morales A +3 more
europepmc +1 more source
The RNA-First Fallacy: Conflating Evolutionary Ancestry with Prebiotic Primacy. [PDF]
Kahana A.
europepmc +1 more source
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Chemical evolution and the evolution of the Earth's crust
Origins of Life and Evolution of Biospheres, 1977It is hypothesized that there is a close relationship between the geologic evolution of the global plates of the Earth's crust and the chemical evolution of life on the Earth. Characteristics of the axes of plate spreading are discussed in relation to postulated environments conductive to the synthesis of chemical compounds thought to be important ...
D E, Ingmanson, M J, Dowler
exaly +3 more sources
2011 IEEE Congress of Evolutionary Computation (CEC), 2011
Chemical methods such as directed evolution and some forms of the SELEX procedure implement evolutionary algorithms directly in vitro. They have a wide range of applications in detecting and targeting diseases and potential applications in other areas as well [1].
In Soo Oh +2 more
openaire +1 more source
Chemical methods such as directed evolution and some forms of the SELEX procedure implement evolutionary algorithms directly in vitro. They have a wide range of applications in detecting and targeting diseases and potential applications in other areas as well [1].
In Soo Oh +2 more
openaire +1 more source
Evolution was Chemically Constrained
Journal of Theoretical Biology, 2003The objective of this paper is to present a systems view of the major features of biological evolution based upon changes in internal chemistry and uses of cellular space, both of which it will be stated were dependent on the changing chemical environment.
R J P, Williams +1 more
openaire +2 more sources

