Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
Core metamorphism controls the dynamic habitability of mid-sized ocean worlds-The case of Ceres. [PDF]
Courville SW+4 more
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Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Lattice Boltzmann simulation for phase separation with chemical reaction controlled by ultrasound field. [PDF]
Wang H, Lu Y.
europepmc +1 more source
Electrically modulated photothermal force microscopy for revealing molecular conformation changes during polarization switching at the nanoscale. [PDF]
Yao S+7 more
europepmc +1 more source
Determining kinetics of H<sub>2</sub>O<sub>2</sub> evolution from photoelectrochemical water oxidation. [PDF]
Li D+8 more
europepmc +1 more source
Advanced architectures of electrochemical interfaces. [PDF]
Zhang W+3 more
europepmc +1 more source
Correction to Role of pKa of Nucleobases in the Origins of Chemical Evolution [PDF]
europepmc +1 more source
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Chemical Evolution of Galaxies
Annual Review of Astronomy and Astrophysics, 1976The various nucleosynthetic processes needed to account for the formation of the different nuclear species have been described in the previous chapters as well as the location of these nucleosynthetic events. At the beginning of this monograph, the evolution of the matter which constitutes the celestial bodies such as planets, stars and galaxies was ...
Audouze, J., Tinsley, B.M.
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Evolution was Chemically Constrained
Journal of Theoretical Biology, 2003The objective of this paper is to present a systems view of the major features of biological evolution based upon changes in internal chemistry and uses of cellular space, both of which it will be stated were dependent on the changing chemical environment.
R. J. P. Williams+1 more
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