Results 301 to 310 of about 7,604,095 (315)

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Towards origins of virtual artificial life: an overview. [PDF]

Philos Trans R Soc Lond B Biol Sci
Stepney S.
europepmc   +1 more source

Can the origin of biosynthetic routes be explained by a Frankenstein's monster-like spontaneous assembly of prebiotic reactants? [PDF]

Philos Trans R Soc Lond B Biol Sci
Negrón-Mendoza A, Hernández-Morales R, Lazcano A.   +2 more
europepmc   +1 more source

Nonequilibrium chemical short-range order in metallic alloys. [PDF]

Nat Commun
Islam M, Sheriff K, Cao Y, Freitas R.
europepmc   +1 more source

Correction to Role of pKa of Nucleobases in the Origins of Chemical Evolution [PDF]

Acc Chem Res, 2013
europepmc   +1 more source

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Chemical and Structural Evolution of AgCu Catalysts in Electrochemical CO2 Reduction.

Journal of the American Chemical Society, 2023
Silver-copper (AgCu) bimetallic catalysts hold great potential for electrochemical carbon dioxide reduction reaction (CO2RR), which is a promising way to realize the goal of carbon neutrality. Although a wide variety of AgCu catalysts have been developed
Peng-Cheng Chen, Chubai Chen, Yao Yang, A. Maulana, Jianbo Jin, J. Feijóo, P. Yang   +6 more
semanticscholar   +1 more source

The Dominant Role of Oxygen in Modulating the Chemical Evolution Pathways of Tyrosine in Peptides: Dityrosine or Melanin.

Angewandte Chemie, 2019
In diverse biological systems, the oxidation of tyrosine to melanin or dityrosine is crucial for the formation of crosslinked proteins and thus for the realization of their structural, biological, and photoactive functionalities; however, the predominant
Xiaokang Ren, Qianli Zou, Chengqian Yuan, Rui Chang, Ruirui Xing, Xuehai Yan   +5 more
semanticscholar   +1 more source

Introduction: Chemical Evolution and the Origins of Life.

Chemical Reviews, 2020
R. Krishnamurthy, N. Hud
semanticscholar   +1 more source

Chemical Evolution

Chemistry and industry, 2020

semanticscholar   +1 more source