Results 261 to 270 of about 15,869,778 (313)

Chemical Bonding in Group III Nitrides

Journal of the American Chemical Society, 2002
We analyze in this article the evolution of the chemical bonding in group III nitrides (MN, M = Al, Ga, In), from the N-N bond dominated small clusters to the M-N bond dominated crystals, with the aim of explaining how the strong multiple bond of N(2) is destabilized with the increase in coordination.
Aurora, Costales, Miguel A, Blanco, Angel, Martín Pendás, Anil K, Kandalam, Ravindra, Pandey   +4 more
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Chemical modifications of amino groups of trypsin

Biochemical and Biophysical Research Communications, 1969
Abstract Reactivity of amino groups of chromatographically homogenious β-trypsin was studied by chemical modification. Guanidination by 1-amidinyl-3, 5-dimethyl pyrazole nitrate led to modification of 10 out of 14 lysyl residues per molecule of trypsin. The guanidinating reagent was found to be a competitive inhibitor of trypsin.
A, Nureddin, T, Inagami
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Chemical Modifications of the Tryptophan Groups of Transferrin

European Journal of Biochemistry, 1972
The tryptophan contents of human serum transferrin and human lactotransferrin have been estimated by colorimetric and spectrophotometric procedures. The nine tryptophan residues of human serum transferrin have been modified by 2‐nitrophenylsulphenyl chloride in 30% acetic acid, 2‐hydroxy‐5‐nitrobenzyl bromide at pH 3 and dimethyl‐(2‐hydroxy‐5 ...
A W, Ford-Hutchinson, D J, Perkins
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A Group Motivational Treatment for Chemical Dependency

Journal of Substance Abuse Treatment, 1999
Patient "motivation" has been implicated as a critical component in addiction treatment outcomes. To date, treatments utilizing motivational elements have been conducted as individual interventions. We describe the development of a Group Motivational Intervention (GMI), a four-session, manual-driven group approach that employs key hypothesized ...
J, Foote, A, DeLuca, S, Magura, A, Warner, A, Grand, A, Rosenblum, S, Stahl   +6 more
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Nucleosides containing chemically reactive groups

Journal of Medicinal Chemistry, 1981
5'-Amino-5'-deoxyinosine (1) and 1-(6-amino-2,5,6-trideoxy-beta-D-erythro-hexofuranosyl)thymine (9) were prepared and substituted on the amino group with chemically reactive functions in an effort to find inhibitors of enzymes that metabolize the corresponding nucleotides.
R D, Elliott, R W, Brockman, J A, Montgomery   +2 more
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Highly Chemically Stable MOFs with Trifluoromethyl Groups: Effect of Position of Trifluoromethyl Groups on Chemical Stability

Inorganic Chemistry, 2019
Metal-organic frameworks (MOFs) are a class of advanced porous crystalline materials. However, numerous MOFs have poor chemical stability, significantly restricting their industrial application. The introduction of trifluoromethyl groups around clusters of MOFs results in a shielding effect caused by their hydrophobicity and bulkiness, thus preventing ...
Keke Wang, Hongliang Huang, Xiaocong Zhou, Qin Wang, Guijie Li, Haimin Shen, Yuanbin She, Chongli Zhong   +7 more
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Prediction of drug target groups based on chemical–chemical similarities and chemical–chemical/protein connections

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014
Drug-target interaction is a key research topic in drug discovery since correct identification of target proteins of drug candidates can help screen out those with unacceptable toxicities, thereby saving expense. In this study, we developed a novel computational approach to predict drug target groups that may reduce the number of candidate target ...
Lei, Chen, Jing, Lu, Xiaomin, Luo, Kai-Yan, Feng   +3 more
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Assessment of Methodology and Chemical Group Dependences in the Calculation of the pK_a for Several Chemical Groups

Journal of Chemical Theory and Computation, 2017
We have investigated the dependencies of various computational methods in the calculation of acid dissociation constants (pKa values) of certain chemical groups found in protonatable amino acids based on our previous scheme [ Matsui ; Phys. Chem. Chem. Phys. 2012 , 14 , 4181 - 4187 ].
Toru Matsui, Yasuteru Shigeta, Kenji Morihashi   +2 more
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On Oxygen‐Containing Groups in Chemically Modified Graphenes

Chemistry – A European Journal, 2012
AbstractReduced graphenes (belonging to the class of chemically modified graphenes, CMG) are one of the most investigated and utilized materials in current research. Oxygen functionalities on the CMG surfaces have dramatic influences on material properties. Interestingly, these functionalities are rarely comprehensively characterized.
Bonanni, Alessandra, Ambrosi, Adriano, Pumera, Martin   +2 more
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On Flupentixol, an Antidepressant of a New Chemical Group

British Journal of Psychiatry, 1969
All hitherto applied antidepressant drugs, both the tricyclic compounds and the MAO inhibitors, present serious disadvantages, not only some more or less grave undesirable side-effects, but also a rather long latency time before the antidepressant effect itself strikes through.
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