Results 91 to 100 of about 7,468,932 (307)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Life-Cycle Risk Assessment of Second-Generation Cellulose Nanomaterials
NanomaterialsA nanomaterial life-cycle risk assessment (Nano LCRA) was conducted for second-generation functionalized cellulose nanomaterials (CNs) in five case studies, including applications in water filtration, food contact packaging (including as an additive and ...
James D. Ede +8 more
doaj +1 more source
Frontiers in Public HealthIntroductionAcute and long-term health impacts from flooding related toxic chemical releases are a significant local health concern and can disproportionately impact communities with vulnerable populations; reliable release data are needed to quantify this hazard.MethodsIn this paper, we analyze US Federal Emergency Management Agency designated ...
Kristin Osiecki +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Survey of common factors to determine suitability for work release
, 1969 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on June 20, 2016)."Work release
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Development of Chemical Reactivity Hazard Tool For Process Safety System [PDF]
, 2011 The major hazards with which the chemical industry is concerned are fire, explosion and toxic release. All the hazard in the chemical industry can be relate to their reactivity.
Ahmad Syafiq B Zahid, Ahmad Syafiq
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Chemical Engineering TransactionsOne of the reasons for the shelter-in-place (SIP) strategy is not often adopted in chemical industries is the lack of methods that can effectively guide evacuees to make the optimal evacuation decision.
Zhichao He +4 more
doaj
Advanced Energy & Sustainability ResearchBlack mass (BM), the key intermediate product in lithium‐ion battery (LIB) recycling, exhibits a complex hazard profile due to its heterogeneous composition, fine particle size, and reactive electrolyte residues.
Alberto Mannu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source