Results 111 to 120 of about 7,468,932 (307)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Ecology and EvolutionAmphibians are increasingly threatened by human activities, with rice straw burning emerging as a significant yet underexplored hazard. This practice may release harmful polycyclic aromatic hydrocarbons (PAHs), disrupt ecosystems, and affect amphibians ...
Qing Tong +7 more
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Revenue Insurance and Chemical Input Use Rates [PDF]
Using farm level data and a simultaneous probit model we evaluate the input use and environmental effects of revenue insurance. A priori, the moral hazard effect on input use is indeterminate and this study empirically assesses the input use impact of ...
Mishra, Ashok K., Nimon, R. Wesley
core
Technological Hazard Characterization
, 2017 In the framework of Natech risk assessment, technological hazard refers to a potential for the occurrence of adverse effects due to the release of hazardous substances, from process or storage equipment, caused by natural-hazard impacts.
Cozzani, V. +3 more
core +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Application of the Simplified Dow Chemical Company Relative Ranking Hazard Assessment Method for Air Combat Command Bases [PDF]
, 1993 This study investigates the possibility of determining the hazard potential of chemicals on Air Force bases using a relative ranking hazard assessment method. Hazard assessment includes identification of hazards and evaluation of the hazards.
Sable, Raymond A.
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Hazard Identification of Liquid Hydrogen in Transfer Operations
Chemical Engineering TransactionsThis paper presents a hazard identification analysis for Liquid Hydrogen (LH2) in transfer operations, focusing on identifying sources of LH2 release and the associated initiating events.
Olga Aneziris +3 more
doaj
Ecotoxicology and Environmental SafetyGraphene-related materials (GRMs) are used in many innovative applications for their outstanding physico-chemical properties. Their possible release could have critical consequences for the environment.
Giada Caorsi +7 more
doaj +1 more source