Results 61 to 70 of about 34,019 (262)

Food biochemistry and related diseases / A bioquímica dos alimentos e doenças relacionadas

Diversitas Journal, 2017
Biochemistry in the kitchen aims to explore the chemical composition of foods and diseases that are related to these chemical components. Among the foods are outstanding for their nutritional value and important for man the sweeteners, milk and bread ...
Millena de Araujo Rodrigues, Bismark da Silva Ferreira, Marcos Ferreira da Silva, Marília Layse Alves da Costa, Anderson Soares de Almeida, Aldenir Feitosa dos Santos   +5 more
doaj   +1 more source

Intolerance to ambient odors at an early stage of pregnancy

, 2007
Adverse reactions to ambient odorous and pungent substances in daily activities among pregnant women who are half-way through pregnancy, and changes in odor perception at predominantly an early stage of pregnancy motivated the present study of odor ...
Nordin, Steven,, Wulff, Marianne,, Bringlöv, Eva,, Broman, Daniel,   +3 more
core   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Intolerance to environmental chemicals and sounds in irritable bowel syndrome : explained by central sensitization?

, 2018
This study tested the hypotheses of irritable bowel syndrome showing (1) comorbidity with chemical and sound intolerance, other types of functionally somatic syndromes, and psychiatric disorders and (2) stronger than normal affective reactions to and ...
Nordin, Steven,, Ståhlberg, Linnea,, Palmquist, Eva,   +2 more
core   +1 more source

Electrothermal Strategies for Upcycling Commodity Plastics

Carbon and Hydrogen, EarlyView.
Future development directions for electrothermal plastic upcycling. (1) Advanced catalyst design and in situ technology development; (2) AI‐assisted reaction process control and catalyst development; (3) Reactor scale‐up and optimization for real‐world plastic feedstock processing; and (4) Integration with renewable electricity and distributed energy ...
Zhe Wang, Chaoping Xu, Zhengwu Yang, Haoyu Yan, Yuming Gao, Jianing Guo, Songbo Yang, Han Hao, Jianhong Gong, Hongsheng Liu, Bo Jiang   +10 more
wiley   +1 more source

Idiopathic Environmental Intolerance: A comprehensive model [PDF]

, 2017
Idiopathic environmental intolerance refers to a group of poorly understood health conditions characterized by heterogeneous somatic symptoms that occur in response to environmental triggers, but for which no physiological causes can be found.
Witthöft, M., Petersen, Sibylle, Van den Bergh, Omer, Brown, Richard; id_orcid, Brown, R.J., Sibylle Petersen, Richard J. Brown, Michael Witthöft, Witthöft, Michael, Omer Van den Bergh, Brown, Richard   +10 more
core   +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source