Results 101 to 110 of about 13,159 (295)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Engineering scale-up and environmental effects of the calcium looping cycle for post-combustion carbon dioxide capture

, 2013
This thesis has addressed several gaps in the knowledge with regards to the calcium looping cycle for carbon dioxide capture, including identification of engineering challenges associated with the scale-up of the technology to pilot scale and beyond ...
Cotton, Alissa
core  

Oxygen Carrying Particle Characterization in Lignocellulosic Fueled Chemical Looping [PDF]

, 2013
The growing awareness of climate change due to anthropogenic CO2 emissions has started a search for clean and renewable energy sources. The chemical looping process is an emerging technology that has potential for high energy efficiency and simultaneous ...
Cilliers, Cornelius
core  

Investigations into the effects of volatile biomass tar on the performance of Fe-based CLC oxygen carrier materials

Environmental Research Letters, 2016
In this study we present findings from investigations into interactions between biomass tar and two iron based oxygen carrier materials (OCMs) designed for chemical-looping applications: a 100% Fe _2 O _3 (100Fe) OCM and a 60 wt% Fe _2 O _3 /40 wt% Al _2
Matthew E Boot-Handford, Nick Florin, Paul S Fennell   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Thermodynamic evaluation of a Ca-Cu looping post-combustion CO2 capture system integrated with thermochemical recuperation based on steam methane reforming

Case Studies in Thermal Engineering
The calcium looping integrated with the chemical looping combustion (CaL-CLC) process is an efficient and cost-effective CO2 capture technology that avoids the energy-intensive air separation unit in the calcium looping (CaL) process.
Song He, Yawen Zheng, Xuelan Zeng, Junyao Wang, Lifan Gao, Dongtai Yang   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Chemical looping : a technology platform for upcycling low-grade industrial resources

, 2023
Ambitions towards a circular economy are increasingly vocalised across academia, policymaking and industry. The endeavour of realising these ambitions provides major opportunities and challenges in chemical engineering, and requires a tremendous roll-out
Buelens, LukasTW110001204673308020018582910000-0002-4896-149807EB0864-F0EF-11E1-A197-91C894A0A6B4, Poelman, HildeTW118010007711080000-0003-4267-7397F47DEEAA-F0ED-11E1-A9DE-61C894A0A6B4, Marin, GuyCA01TW118010004530280000-0002-6733-1213F40153D6-F0ED-11E1-A9DE-61C894A0A6B4, Galvita, VladimirTW110001712325818020005981030000-0001-9205-79171E4688D2-F0EE-11E1-A9DE-61C894A0A6B4, Singh, Varun0001709903848020026893609727863643050000-0001-5655-14830386E7B2-973D-11E7-93F3-FBB4AD28A064   +4 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Chemical Looping Technologies for H₂ Production with CO₂ Capture:Thermodynamic Assessment and Economic Comparison [PDF]

, 2017
This work addresses the techno-economic assessment of two chemical looping technologies for H2 production from natural gas fully integrated with CO2 capture.
Martin van Sint Annaland, Spallina, V., Alessandro Battistella, Spallina, Vincenzo, Spallina, Vincenzo; id_orcid, Battistella, Alessandro, Sint Annaland, M Martin van, Spallina, V Vincenzo, Shams, Ahmed, Gallucci, F Fausto, Gallucci, F., Annaland, Martin Van Sint, van Sint Annaland, M., Gallucci, F.; id_orcid, Battistella, A Alessandro, Gallucci, Fausto, Vincenzo Spallina, Fausto Gallucci, Ahmed Shams, Shams, A., Battistella, A., Shams, A   +21 more
core   +1 more source