Results 71 to 80 of about 13,159 (295)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Chemical Looping Co-Gasification Characteristics of Cyanobacterial/Coal Blends

Energies, 2020
The frequent outbreak of cyanobacteria bloom results in an urgent need for the resource utilization of cyanobacteria. However, the development of routine thermal treatment (i.e., gasification and pyrolysis) is hindered by the issue of high moisture ...
Tianxu Shen, Jiang Zhang, Laihong Shen, Lei Bai, Jingchun Yan   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Recent Advances in the Evolution of Pollutants and Their Interactions with Oxygen Carriers During Coal Chemical Looping

Atmosphere
Chemical looping is a clean, energy-efficient, and economically viable route for coal utilization. However, the pyrolysis and gasification of raw coal in chemical looping generate gaseous pollutants (SOX, NOX, and Hg) and ash that affect both reactor ...
Yudong Pang, Shien Liu, Chungang Li, Mei An, Guodong Zhang   +4 more
doaj   +1 more source

Automated discovery of novel drug formulations using predictive iterated high throughput experimentation. [PDF]

PLoS ONE, 2010
BACKGROUND: We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first ...
Filippo Caschera, Gianluca Gazzola, Mark A Bedau, Carolina Bosch Moreno, Andrew Buchanan, James Cawse, Norman Packard, Martin M Hanczyc   +7 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Packed Bed Reactor Technology for Chemical-Looping Combustion [PDF]

, 2006
Chemical-looping combustion (CLC) has emerged as an alternative for conventional power production processes to intrinsically integrate power production and CO2 capture. In this work a new reactor concept for CLC is proposed, based on dynamically operated
van Sint Annaland, M., Kuipers, J.A.M.; id_orcid, Kuipers, JAM Hans, Noorman, S, Sint Annaland, M Martin van, Kuipers, J.A.M., Sint Annaland, van, M., Noorman, S.   +7 more
core   +1 more source

Machine learning-driven predictive design of catalytic oxygen carriers for chemical looping processes

Discover Energy
Chemical looping is an innovative technology for conversion of fossil fuels to clean energy with integrated carbon dioxide capture. The success of this technology depends on the performance of oxygen carriers which circulate between the reactors. However,
Zhuo Cheng, Qichang Meng, Xiaofeng Jiang, Sudeshna Gun, Liang-Shih Fan   +4 more
doaj   +1 more source

Numerical simulations of fluidization dynamics in a hot model of a CLC process

E3S Web of Conferences, 2017
Chemical Looping Combustion (CLC) is one of the most promising alternatives for solid fuel combustion. CO2 concentration in the exhaust gas is high in CLC technology which enables high efficiency of CO2 capture from flue gas.
Żyłka Anna, Krzywański Jarosław, Czakiert Tomasz, Idziak Kamil, Kulicki Krzysztof, Jankowska Sylwia, Nowak Wojciech   +6 more
doaj   +1 more source