Results 51 to 60 of about 59,379 (275)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Efficacy and Safety of 40% Glycolic Acid Peels in patients with Melasma [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2018
Objective: To determine the efficacy and safety of 40% glycolic acid peels in patients with melasma in Asian Skin. Methodology: Sixty patients of either gender with melasma of any type (epidermal, dermal, and mixed); having Fitzpatrick's skin type IV ...
Uzma Ahsan , Samina Khan, Ammara Azeem
doaj  

Adhesion mechanics of graphene membranes

open access: yes, 2012
The interaction of graphene with neighboring materials and structures plays an important role in its behavior, both scientifically and technologically.
Aitken   +49 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Phase stability analysis in Fe-Pt and Co-Pt alloy systems: An augmented space study

open access: yes, 2004
We have studied the problem of phase stability in Fe-Pt and Co-Pt alloy systems. We have used the orbital peeling technique in the conjunction of augmented space recursion based on the tight binding linear orbital method as the method for the calculation
Abhijit Mookerjee   +20 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

A study comparing chemical peeling using modified jessner′s solution and 15% trichloroacetic acid versus 15% trichloroacetic acid in the treatment of melasma

open access: yesIndian Journal of Dermatology, 2009
Background: Melasma is a symmetric progressive hyperpigmentation of the facial skin that occurs in all races but has a predilection for darker skin phenotypes.
Safoury Omar   +3 more
doaj  

Keperluan perkmdmatan e-kaunseling berasaskan laman web dikalangan pelajar sarjana pendidikan teknik dan vokasional (PTV) dI KUiTTHO [PDF]

open access: yes, 2002
Kajian ini bertujuan mengetahui keperluan kaunseling berasaskan laman web yang digunakan sebagai medium perantaraan dalam sesi kaunseling. Ia adalah satu alternatif bagi menyokong kepada kaunseling secara bersemuka.
Abdul Manah, Mohd Hoirie
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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