Results 161 to 170 of about 1,196,417 (299)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Green Condensation of Aromatic Aldehydes and Barbituric Acid Enabled by Spiral Gas-Solid Flow. [PDF]

ACS Omega
Xiao Z, Song Y, Zhang J, Cai B, Lan X, Lv G, Peng R, Jin B.   +7 more
europepmc   +1 more source

QUANTITATIVE MODELLING OF CHEMICAL REACTIONS 1. QUANTITATIVE APPROACH TO INVESTIGATING COMPLEX CHEMICAL REACTIONS. A CONVERSION MODEL OF REACTION [PDF]

Proceedings of the Academy of Sciences of the Estonian SSR. Chemistry, 1989
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Solvent-temperature coupled hydride transfer controls product selectivity in the HSiR₃/KO ^<i>t</i> Bu catalytic system. [PDF]

Chem Sci
Yao H, Zhou Z, Liu Y, Zhang DH, Li G.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Chemical Graph-Based Transformer Models for Yield Prediction of High-Throughput Cross-Coupling Reaction Datasets

ACS Omega
Akinori Sato, Ryosuke Asahara, Tomoyuki Miyao   +2 more
doaj   +1 more source

Synergizing Chemical and AI Communities for Advancing Laboratories of the Future. [PDF]

ACS Cent Sci
Oh S, Fang X, Lin IH, Dee P, Dunham CS, Copp SM, Doyle AG, Read de Alaniz J, Gu M.   +8 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Atomistic insights into the degradation of perfluorosulfonic acid membranes: A reactive force field molecular dynamics study. [PDF]

PLoS One
Qi W, Li Y, Ruan S, Gui X, Xu Y, Lu H.
europepmc   +1 more source