FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Enhancing Molecular High-Pressure Simulations by Implicit Solvation. [PDF]
J Phys Chem AKißing N, Zeller F, Neudecker T.
europepmc +1 more source
Local and global stability of equilibria for a class of chemical reaction networks
, 2013 Donnell, Pete, Banaji, Murad
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Competitive roles of plasticity, elasticity, and radiation in heat/mass transfer of Casson-Williamson-Maxwell nanofluid over a porous stretching sheet. [PDF]
Discov NanoKavitha R, Samikannu R, Ladu NSD.
europepmc +1 more source
QUANTITATIVE MODELLING OF CHEMICAL REACTIONS 1. QUANTITATIVE APPROACH TO INVESTIGATING COMPLEX CHEMICAL REACTIONS. A CONVERSION MODEL OF REACTION [PDF]
Proceedings of the Academy of Sciences of the Estonian SSR. Chemistry, 1989 openaire +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Neutralization Kinetics and Transport Define the Dermal Decontamination Window for Warfare and Industrial Toxicants. [PDF]
Chem Res ToxicolSimon L, Kulkarni I.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Yield Prediction of Organic Reactions in Biased Data Sets via Positive-Unlabeled Learning. [PDF]
J Am Chem SocBoser F, Spies JC, Glorius F.
europepmc +1 more source