Results 81 to 90 of about 617,908 (340)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
A detailed balanced reaction network is sufficient but not necessary for its Markov chain to be detailed balanced [PDF]
, 2013 Certain chemical reaction networks (CRNs) when modeled as a deterministic dynamical system taken with mass-action kinetics have the property of reaction network detailed balance (RNDB) which is achieved by imposing network-related constraints on the ...
Badal Joshi
semanticscholar +1 more source
Graph-Driven Reaction Discovery: Progress, Challenges, and Future Opportunities
Journal of Physical Chemistry A, 2022 Graph-based descriptors, such as bond-order matrices and adjacency matrices, offer a simple and compact way of categorizing molecular structures; furthermore, such descriptors can be readily used to catalog chemical reactions (i.e., bond-making and ...
I. Ismail +2 more
semanticscholar +1 more source
The genealogical tree of ethanol: gas-phase formation of glycolaldehyde, acetic acid and formic acid [PDF]
, 2017 Despite the harsh conditions of the interstellar medium, chemistry thrives in it, especially in star forming regions where several interstellar complex organic molecules (iCOMs) have been detected. Yet, how these species are synthesised is a mystery. The
Balucani, Nadia +7 more
core +4 more sources
Modeling the Impact of Moderate External UV Irradiation on Disk Chemistry
The Astrophysical JournalThe chemistry within a protoplanetary disk is greatly affected by external radiation from the local stellar environment. Previous work has focused on extreme radiation fields, representative of the center of something like the Orion Nebula Cluster ...
Rachel E. Gross, L. Ilsedore Cleeves
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Water formation at low temperatures by surface O2 hydrogenation II: the reaction network
, 2010 Water is abundantly present in the Universe. It is the main component of interstellar ice mantles and a key ingredient for life. Water in space is mainly formed through surface reactions.
Acharyya +38 more
core +1 more source
Chemical Engineering Transactions, 2013 Batch reactors are widely used in the polymer industry, especially for multi-purpose processes where different types of polymers are produced on demand.
R. Ribeiro Santos +4 more
doaj +1 more source
Extreme learning with chemical reaction optimization for stock volatility prediction
Financial Innovation, 2020 Extreme learning machine (ELM) allows for fast learning and better generalization performance than conventional gradient-based learning. However, the possible inclusion of non-optimal weight and bias due to random selection and the need for more hidden ...
Sarat Chandra Nayak, Bijan Bihari Misra
doaj +1 more source
Self-Organization and Genomic Causality in Models of Morphogenesis
Entropy, 2023 The debate about what causes the generation of form and structure in embryological development goes back to antiquity. Most recently, it has focused on the divergent views as to whether the generation of patterns and form in development is a largely self-
Ute Deichmann
doaj +1 more source