Results 211 to 220 of about 6,987,585 (297)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Tandem Oxidative α‑Hydroxylation/β-Acetalization Reaction of β‑Ketoamides and Its Applications

ACS Omega, 2017
Zhiguo Zhang, Xiaolong Gao, Haifeng Yu, Jingjing Bi, Guisheng Zhang   +4 more
doaj   +1 more source

Exploring the Balance between Faradaic and Non-Faradaic Processes in Organic Chemical Reactions at Plasma-Liquid Interfaces. [PDF]

J Am Chem Soc
Bloomquist CK, Naumov D, Yang A, Mathison R, Herzog BD, Tenn WJ, Modestino MA, Aydil ES.   +7 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Quantum information scrambling and chemical reactions. [PDF]

Proc Natl Acad Sci U S A
Zhang C, Kundu S, Makri N, Gruebele M, Wolynes PG.   +4 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Enhancing Ammonium-Ion Storage Capability of NH4V3O8 via an Interlayer Defect-Modulation Strategy

ACS Omega
Yu-Ting Wang, Pengcheng Su, Kang Zhang, Duolin Xu, Wenhui Chen, Mengyan Zhang, Hongwei Tang, Yihui Li   +7 more
doaj   +1 more source

Dynamics of chemical reactions and temperature-dependent thermal conductivity in a viscous fluid over an oscillating curved surface. [PDF]

Sci Prog
Naveed M, Imran M, Imran M, Khadim F.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Pore Network Modeling of Intraparticle Transport Phenomena Accompanied by Chemical Reactions. [PDF]

Ind Eng Chem Res
Fathiganjehlou A, Peters EAJF, Buist KA, Kuipers JAM.   +3 more
europepmc   +1 more source