Results 151 to 160 of about 6,218,927 (299)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

REACTIVE CHEMICAL [PDF]

Chemical & Engineering News Archive, 1964
openaire   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Influence of Temperature on Reaction Pathways in Fructose Conversion over Mixed Oxide Catalysts Based on Ce and Nb

ACS Omega
Dhara Beatriz de Amorim Pryston, Thatiane Veríssimo dos Santos Martins, Jailma Barros dos Santos, Daniel Santos Vilela Ferreira, Wemerson do Nascimento Silva, Renato da Silva Ferreira, Maria do Carmo M. Alves, Jonder Morais, Janaína Heberle Bortoluzzi, Mario Roberto Meneghetti, Simoni Margareti Plentz Meneghetti   +10 more
doaj   +1 more source

Theoretical study of chemical reactivity descriptors of some repurposed drugs for COVID-19. [PDF]

MRS Adv, 2023
Morad R, Akbari M, Maaza M.
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Chemical Reactivity

Journal of Chemical Sciences, 2005
openaire   +2 more sources

Molecular orbital node engineering in pyrene: linking chemical reactivity with room-temperature phosphorescence. [PDF]

Natl Sci Rev
Liu H, Zhou D, Zhang W, Zhang X, Yang C, Zhang B, Cheng A, Su H, Zhang Y, Zhou M, Zhang X, Wang T, Zhang G.   +12 more
europepmc   +1 more source

Computational Insights on the Chemical Reactivity of Functionalized and Crosslinked Polyketones to Cu²⁺ Ion for Wastewater Treatment. [PDF]

Polymers (Basel), 2023
Ortega DE, Cortés-Arriagada D, Araya-Hermosilla R.   +2 more
europepmc   +1 more source