BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
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Exploring the chemical reactivity of 2,6-dimethylchromone toward heterocyclic hydrazines and enamines: experimental and theoretical investigations. [PDF]
Abdel-Megid M +3 more
europepmc +1 more source
Chemical reactivity, molecular electrostatic potential and in-silico analysis on benzimidazole fungicide benomyl. [PDF]
Mol GPS, Aruldhas D, Joe IH.
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Study on the chemical reactivity difference of primary hydroxyl groups in iridoid glycosides. [PDF]
Kong Y +6 more
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Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Electronic Structure, Ligand Effects, and Chemical Reactivity of the Ground and Low-Lying Excited Electronic States of NpO<sup>3</sup>. [PDF]
Gregory T, Miliordos E.
europepmc +1 more source
Chemical reactivity of the tryptophan/acetone/DMSO triad system and its potential applications in nanomaterial synthesis. [PDF]
Huang CY, Liao HW, Hu TM.
europepmc +1 more source

