Results 181 to 190 of about 598,568 (300)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Macauba (Acrocomia aculeata) as a Bioenergy Platform: Integrated Biodiesel Production and Lignocellulosic Biomass Valorization

ACS Omega
Daniel Chagas Nascimento, Ewerton Henrique de Souza Santos, Fábio Moreira da Silva, Diego Coelho Barroso dos Santos, Edgar Amaral Silveira, Janaína Heberle Bortoluzzi, Grace Ferreira Ghesti, Mario Roberto Meneghetti, Paulo Anselmo Ziani Suarez, Simoni Margareti Plentz Meneghetti   +9 more
doaj   +1 more source

Chemical reactivity of 2-methylchromone with some nitrogen-based nucleophiles: reactions, DFT analysis, anticancer activity and molecular docking studies. [PDF]

RSC Adv
Abdel-Megid M, Alshaye NA, Badran AS, Ibrahim MA.   +3 more
europepmc   +1 more source

Triplet-driven chemical reactivity of β-carotene and its biological implications. [PDF]

Nat Commun, 2022
Zbyradowski M, Duda M, Wisniewska-Becker A, Heriyanto, Rajwa W, Fiedor J, Cvetkovic D, Pilch M, Fiedor L.   +8 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Phenomenological Symmetry Rule for Chemical Reactivity Under Vibrational Strong Coupling. [PDF]

Angew Chem Int Ed Engl
Jayachandran A, Patrahau B, Ricca JG, Mahato MK, Pang Y, Nagarajan K, Thomas A, Genet C, Ebbesen TW.   +8 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Chemical reactivity of RNA and its modifications with hydrazine. [PDF]

Commun Chem
Yeşiltaç-Tosun N, Qi Y, Li C, Stafflinger H, Hollnagel K, Rusling L, Wöhnert J, Kaiser S, Kaiser S.   +8 more
europepmc   +1 more source

Automated Variable Electric-Field DFT Application for Evaluation of Optimally Oriented Electric Fields on Chemical Reactivity. [PDF]

J Org Chem, 2023
Hanaway DJ, Kennedy CR.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source