Results 191 to 200 of about 598,568 (300)

Exceptions, Paradoxes, and Their Resolutions in Chemical Reactivity. [PDF]

J Org Chem
Qiu G.
europepmc   +1 more source

Functional asymmetry and chemical reactivity of CsoR family persulfide sensors. [PDF]

Nucleic Acids Res, 2021
Fakhoury JN, Zhang Y, Edmonds KA, Bringas M, Luebke JL, Gonzalez-Gutierrez G, Capdevila DA, Giedroc DP.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

DNA Strand Breaks and Denaturation as Probes of Chemical Reactivity versus Thermal Effects of Atmospheric Pressure Plasma Jets. [PDF]

ACS Omega, 2023
Sebastian A, Lipa D, Ptasinska S.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Evaluating the Chemical Reactivity of Wildfire-Derived Dissolved Organic Molecules: Glutathione Binding through Kendrick Mass Defect Analysis. [PDF]

J Am Soc Mass Spectrom
Hamontree HM, Hatcher PG.
europepmc   +1 more source

Conformational Control of Chemical Reactivity for Surface-Confined Ru-Porphyrins. [PDF]

Angew Chem Int Ed Engl, 2021
Knecht P, Reichert J, Deimel PS, Feulner P, Haag F, Allegretti F, Garnica M, Schwarz M, Auwärter W, Ryan PTP, Lee TL, Duncan DA, Seitsonen AP, Barth JV, Papageorgiou AC.   +14 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Chemical Reactivity Parameters to Analyze Psychedelics: How Do We Explain the Potency of the Drugs? [PDF]

ACS Omega
Martínez A, Caballero A, Ramírez R, Perez-Sanchez E, Quevedo E, Salvador-García D.   +5 more
europepmc   +1 more source

Gradient area-selective deposition for seamless gap-filling in 3D nanostructures through surface chemical reactivity control. [PDF]

Nat Commun, 2022
Nguyen CT, Cho EH, Gu B, Lee S, Kim HS, Park J, Yu NK, Shin S, Shong B, Lee JY, Lee HB.   +10 more
europepmc   +1 more source