Results 71 to 80 of about 6,218,927 (299)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Enhanced Chemical Reactivity of Graphene by Fermi Level Modulation

open access: yes, 2018
Among various approaches to modify the electronic and chemical properties of graphene, functionalization is one of the most facile ways to tailor these properties.
이혁진
core   +1 more source

An autonomous organic reaction search engine for chemical reactivity [PDF]

open access: yes, 2017
The exploration of chemical space for new reactivity, reactions and molecules is limited by the need for separate work-up-separation steps searching for molecules rather than reactivity.
Sans, Victor   +9 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural, spectral, biological and antioxidant analyses of baicalin and ıts vanadium complexes: a dft study

open access: yesCumhuriyet Science Journal, 2020
Molecular simulation analyses of baicalin and its vanadium complexes were done at B3LYP/6-31+G(d) and B3LYP/ANL2DZ levels, respectively. The conformer analyses were performed for baicalin and the most stable one is determined at OPLS3e method by using ...
Koray Sayın, Ayhan Üngördü
doaj   +1 more source

Thermal stability of nano-KH particles and their chemical reactivities

open access: yes, 2002
The variation of specific surface area and chemical reactivity of nano-KH particles treated at different temperatures has been studied, The BET surface area of nano-KH decreases with the increase of heat treatment temperature, while the chemical ...
Wang, FD   +4 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Conceptual DFT Study of the Local Chemical Reactivity of the Colored BISARG Melanoidin and Its Protonated Derivative

open access: yesFrontiers in Chemistry, 2018
This computational study assessed eight fixed RSH (range-separated hybrid) density functionals that include CAM-B3LYP, LC-ωPBE, M11, MN12SX, N12SX, ωB97, ωB97X, and ωB97XD related to the Def2TZVP basis sets together with the SMD solvation model in the ...
Juan Frau   +2 more
doaj   +1 more source

The role of charge transfer in the stability and reactivity of chemical systems from experimental findings

open access: yes, 2017
Phenomena are described within a unifying picture, by isolating charge/electron transfer as an interaction component triggering chemical reactivity.
S. Falcinelli   +7 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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