Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Research orientations in design for recovery applied to composite parts [PDF]
, 2011 The composite use in industry increases. Despite, composite end of life solutions are still under development. We proposed to address a combined definition of both composite design and composite recycling process.
MANTAUX, Olivier +3 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
An innovative data-driven approach to the design and optimization of battery recycling processes [PDF]
Publisher Copyright: © 2025 The Author(s)With the growing demand for raw materials to enable the ongoing electrification transition, robust battery recycling technologies will also become necessary to reduce reliance on primary resources and improve ...
Todorović, Milica +4 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Enabling the Circular Economy through Chemical Recycling and Upcycling of End-of-Use Plastics
, 2022 Widespread plastic pollution has led to an environmental crisis, motivating new and effective methods for recycling and upcycling “end-of-use” plastics.
Ryan, Helmer +6 more
core +1 more source
Chemical recycling of plastic wastes via homogeneous catalysis: A review
Improper disposal of plastic wastes causes serious negative impacts on the ecosystem. These plastic wastes are considered to be a rich carbon resource, and the use of homogeneous catalytic chemical recycling methods has enabled the high-value recovery of
Yuan, Haoran +4 more
core +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Sustainable strategies for crystalline solar cell recycling: A review on recycling techniques, companies, and environmental impact analysis [PDF]
Solar PV is gaining increasing importance in the worldwide energy industry. Consequently, the global expansion of crystalline photovoltaic power plants has resulted in a rise in PV waste generation.
Akhter, Mina +13 more
core +1 more source