Results 61 to 70 of about 5,647,860 (252)

Research orientations in design for recovery applied to composite parts [PDF]

, 2011
The composite use in industry increases. Despite, composite end of life solutions are still under development. We proposed to address a combined definition of both composite design and composite recycling process.
MANTAUX, Olivier, KROMM, François-Xavier, POMPIDOU, Stéphane, PERRY, Nicolas   +3 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Towards the production of oxalate precursors from NMC111 black mass via selective leaching of Li and Al and solvent extraction of Cu

Journal of Power Sources Advances
A novel recycling route for spent lithium-ion batteries has been investigated. The end goal is to produce cathode active material (CAM) precursor directly from the recycled solution.
Léa Marie Jacqueline Rouquette, Laura Altenschmidt, Camille Travert, Andrea Locati, William R. Brant, Martina Petranikova   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Characteristics and Material Flows of Diary Packaging in Municipal Solid Waste: A Case Study of Plastic Yoghurt Cups in Vienna

Global Challenges
Yoghurt cup packaging has received increasing attention regarding design‐for‐recycling. Packaging technologies like the three‐component (3C) cup, consisting of a plastic cup, carton wrap and aluminum cover, reduce the amount of plastic needed.
Gisela Breslmayer, Lea Gritsch, Jakob Lederer   +2 more
doaj   +1 more source

Platinum Compound on Gold–Magnesia Hybrid Structure: A Theoretical Investigation on Adsorption, Hydrolysis, and Interaction with DNA Purine Bases

Nanomaterials
Cisplatin-based platinum compounds are important clinical chemotherapeutic agents that participate in most tumor chemotherapy regimens. Through density-functional theory calculations, the formation and stability of the inorganic oxide carrier, the ...
Zhenjun Song, Mingyue Liu, Aiguo Zhong, Meiding Yang, Zhicai He, Wenmin Wang, Hongdao Li   +6 more
doaj   +1 more source

Recycling of poly(ethylene terephthalate) – A review focusing on chemical methods

eXPRESS Polymer Letters, 2016
Recycling of poly(ethylene terephthalate) (PET) is of crucial importance, since worldwide amounts of PETwaste increase rapidly due to its widespread applications. Hence, several methods have been developed, like energetic, material, thermo-mechanical and
B. Geyer, G. Lorenz, A. Kandelbauer
doaj   +1 more source

City of Newark Waste Utilization Study Summary & Plan of Action: Recycling Plan of Action

, 1986
The City of Newark partnered with Self-Reliance, Inc. (SRI) of Washington, D.C., in 1983 to examine waste products and practices in order to reduce waste while stimulating economic development activities.

core   +1 more source