Results 101 to 110 of about 3,025,562 (306)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

(Z)-3-(3,4-Dimethoxyphenyl)-3-(4-fluorophenyl)-1-morpholinoprop-2-en-1-one

open access: yesActa Crystallographica Section E, 2011
The title compound, C21H22FNO4, is an isomer of flumorph (systematic name 4-[3-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-oxo-2-propenyl]morpholine), which was developed by Shenyang research institute of chemical industry and used as fungicide.
Baoshan Chai, Changling Liu
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Para amino benzoic acid-derived self-assembled biocompatible nanoparticles for efficient delivery of siRNA

open access: yesInternational Journal of Nanomedicine, 2015
Teegala Lakshminarayan Reddy,1,5 P Sivarama Krishnarao,2 Garikapati Koteswara Rao,1,5 Eswar Bhimireddy,2 P Venkateswarlu,4 Debendra K Mohapatra,2,5 JS Yadav,2 Utpal Bhadra,3 Manika Pal Bhadra1,5 1Centre for Chemical Biology, CSIR-Indian Institute of ...
Reddy TL   +8 more
doaj  

Biomedical Research Involving Prisoners: Ethical Values and Legal Regulation [PDF]

open access: yes, 2007
Until the early 1970\u27s, approximately 90% of all pharmaceutical research was conducted on prisoners, who were also subjected to biochemical research, including studies involving dioxin and chemical warfare agents.
Gostin, Lawrence O.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Women in chemistry: Q&A with Dr Laura Cattaneo

open access: yesCommunications Chemistry
Dr Laura Cattaneo is a group leader at the Max Planck Institute for Nuclear Physics in Heidelberg, Germany. She has an interdisciplinary research background in chemical physics, connecting materials science, liquid crystals, and ultrafast processes in ...
doaj   +1 more source

Methods for verifying the authenticity of hops – an effective tool against falsification

open access: yesKvasný průmysl, 2016
Falsifi cation attempts occur in almost all commodities and hops is no exception. It is therefore necessary to look for ways to verify its authenticity.
Jana Olšovská   +4 more
doaj  

Contribution of the 33 Central Scientific Research Test Institute of the Ministry of Defence of the Russian Federation to the Victory over Nazi Germany in the Great Patriotic War

open access: yesВестник войск РХБ защиты
Highlights In 1941–1945 experts of Research Chemical Institute (RCI RAPW) and Central Military Chemical Test Site (CMCTS) created brand-new samples of chemical protection devices (respirators, protective suits, chemical-warfare decontamination agents ...
A. Yu. Boyko   +2 more
doaj   +1 more source

2007 Annual Report Summer Research Institute Interfacial and Condensed Phase Chemical Physics [PDF]

open access: yes, 2007
The Pacific Northwest National Laboratory (PNNL) hosted its fourth annual Summer Research Institute in Interfacial and Condensed Phase Chemical Physics from April through September 2007. During this time, 21 PNNL scientists hosted 23 participants from 20 different universities.
openaire   +2 more sources

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