Results 21 to 30 of about 1,417,488 (251)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Swapna S Shanbhag,1 Sanjay Chanda,1 Pragnya R Donthineni,1 Sayan Basu1– 3 1The Cornea Institute, L.V. Prasad Eye Institute, Hyderabad, Telangana, India; 2Center for Ocular Regeneration (CORE), L.V.
Shanbhag SS +3 more
doaj
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
National Institute of Materials and Chemical Research.
The transition to a symmetric ice has been observed at about 60 GPa by infrared absorption spectroscopy. The hydrogen-bond symmetrization, which is accompanied by a subsequent deformation of the hydrogen-bond potential from a double to single minimum shape, is well recognized as a turn in the pressure dependence of the OH stretching frequencies from a ...
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Laboratory of Radiochemistry at Bern University and the Paul Scherrer Institute
Radiochemical research in Switzerland is pursued in a laboratory jointly financed by Bern University and the Paul Scherrer Institute. Presently, four groups – one at Bern University and three at the Paul Scherrer Institute – perform basic ...
Heinz W. Gäggeler, Urs Krähenbühl
doaj +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Tatsiana V. Gaevskaya +3 more
doaj +1 more source
Strong spin-orbit coupling inducing Autler-Townes effect in lead halide perovskite nanocrystals
Here, Yumoto et al. demonstrate that for a halide perovskite with large spin-orbit splitting the optical Stark effect can give way to a three level Autler-Townes effect in the near-infrared region.
Go Yumoto +6 more
doaj +1 more source

