Results 181 to 190 of about 1,177,372 (244)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Reduced chemical application with bio-organic fertilizer to improve grain filling characteristics and fertilizer partial productivity of highland barley under irrigation regimes. [PDF]

PLoS One
Xu Y, Wang X, Liu J, Zhang Y, Huo K, Chang H.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Regularized regression in ultra-small chemometric datasets: A methodological case study using FTIR spectra of Schiff bases. [PDF]

PLoS One
Rashedi KA, Alshammari TS, Alshammari KM, Alanazi TA, Shabbir J, Mehmood T.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

RETRACTED: Ferlazzo et al. A Flavonoid-Rich Extract from Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, Shows Protective Effects in a Murine Model of Cadmium-Induced Testicular Injury. <i>Pharmaceuticals</i> 2021, <i>14,</i> 386. [PDF]

Pharmaceuticals (Basel)
Ferlazzo N, Micali A, Marini HR, Freni J, Santoro G, Puzzolo D, Squadrito F, Pallio G, Navarra M, Cirmi S, Minutoli L.   +10 more
europepmc   +1 more source

Short-term effects of bone meal powder on soil phosphorus availability, seed germination, and early growth parameters of Malabar Spinach (Basella alba). [PDF]

PLoS One
Roy A, Sarker P.
europepmc   +1 more source

Correction: Application of cinnamon essential oil microcapsules in anti-fungal preservation of Spatholobi caulis. [PDF]

Sci Rep
Gao Y, Jiang C, Xia C, Zhao Y, Kan C.
europepmc   +1 more source

Direct resist-free patterning of an organic semiconductor via thermal scanning probe lithography. [PDF]

Discov Nano
Luo K, Li J, Gu Y, Ma T, Zhang J, Cao L, Zhu Z, Tang H, Xu P, Jia H, Tu M, Li X.   +11 more
europepmc   +1 more source