Results 71 to 80 of about 1,378,218 (287)
STAR ProtocolsSummary: Chiral allenylsilanes serve as crucial intermediates in the synthesis of complex pharmaceutical molecules and natural products. Here, we present a protocol for synthesizing both racemic and chiral allenylsilanes through copper-catalyzed ...
Ying Zhou, Zhengli Liu
doaj +1 more source
Chemical Tools for Studying Directed Cell Migration
, 2011 Cell migration is required for many physiological processes, including wound repair and embryogenesis, and relies on precisely orchestrated events that are regulated in a spatially and temporally controlled manner.
Goguen, Brenda N. +3 more
core +1 more source
Correctable Modeling in Chemical Sciences
, 2020 This contains DFT and experimental data used in the publication titled "Explainable and Trustworthy Artificial Intelligence for Correctable Modeling in Chemical ...
Lansford, Joshua +3 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The science of mesotherapy: Chemical anarchy [PDF]
Aesthetic Surgery Journal, 2006 The author stresses that to date, the effects of mesotherapy have not been scientifically evaluated. Currently, there is no standardization of dosage and no protocol or treatment algorithm to enable prediction of how much tissue or fat will be "dissolved" with a specific solution in a defined quantity, and injected at a specified subcutaneous tissue ...
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
SCS Academy: Course Program Fall 2022
, 2022 The SCS Academy of the SCG offers upgrade training courses in various fields of chemical and pharmaceutical sciences. In addition to the established range of courses in analytics (spectroscopy, separation technology, quality assurance and ...
Swiss Chemical Society
core
Data availability in Chemical Science
Chemical Science, 2021 Introducing Data Availability Statements in Chemical Science.
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2013 Recently, a number of organisations have called for open access to scientific information and especially to the data obtained from publicly funded research, among which the Royal Society report and the European Commission press release are particularly ...
Frey, Jeremy G., Bird, Colin
core +1 more source