Results 131 to 140 of about 187,372 (259)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Light-Sheet Skew Ray-Based Microbubble Chemical Sensor for Pb²⁺ Measurements. [PDF]

Sensors (Basel)
Zhuang T, Xu L, Khalid M, Wu X, Du L, Shahnia S, Codemard CA, Bai Z, Wang Y, Liu S, Chen GY, Wang Y.   +11 more
europepmc   +1 more source

Dual-Ligand Strategy Employing Rigid 2,5-Thiophenedicarboxylate and 1,10-Phenanthroline as Coligands for Solvothermal Synthesis of Eight Lanthanide(III) Coordination Polymers: Structural Diversity, DFT Study, and Exploration of the Luminescent Tb(III) Coordination Polymer as an Efficient Chemical Sensor for Nitroaromatic Compounds. [PDF]

ACS Omega, 2022
Ashashi NA, Nisa ZU, Singhaal R, Sen C, Ahmad M, Frontera A, Sheikh HN.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Facile fabrication of a graphene-based chemical sensor with ultrasensitivity for nitrobenzene. [PDF]

RSC Adv
Raza A, Ullah Z, Khalil A, Batool R, Haider S, Alam K, Sonil NI, Rouf AM, Nazar MF.   +8 more
europepmc   +1 more source

Fabrication of selective and sensitive chemical sensor probe based on ternary nano-formulated CuO/MnO₂/Gd₂O₃ spikes by hydrothermal approach. [PDF]

Sci Rep, 2020
Rahman MM, Rahman MM, Alam MM, Asiri AM, Opo FADM.   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Data-Driven Approach to Modeling Microfabricated Chemical Sensor Manufacturing. [PDF]

Anal Chem
Chew BS, Trinh NN, Koch DT, Borras E, LeVasseur MK, Simms LA, McCartney MM, Gibson P, Kenyon NJ, Davis CE.   +9 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Colorimetric Sensing of Volatile Organic Compounds Produced from Heated Cooking Oils

ACS Omega, 2021
Emer Duffy, Emme Cauven, Aoife Morrin
doaj   +1 more source