Results 91 to 100 of about 1,635,553 (300)

Solution Structures of \u3cem\u3eMycobacterium tuberculosis\u3c/em\u3e Thioredoxin C and Models of Intact Thioredoxin System Suggest New Approaches to Inhibitor and Drug Design [PDF]

, 2013
Here, we report the NMR solution structures of Mycobacterium tuberculosis (M. tuberculosis) thioredoxin C in both oxidized and reduced states, with discussion of structural changes that occur in going between redox states.
Cai, Sheng, Neumann, Terrence S., Olson, Andrew Lawrence, Sem, Daniel S.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Three-Dimensional Structures of 3/4/5-O-feruloylquinic Acids by NMR Spectroscopy and Quantum Chemistry Calculation

Chinese Journal of Magnetic Resonance
3/4/5-O-feruloylquinic acids (3/4/5-O-FQA) have antioxidant activity, which is beneficial to disease prevention and human health maintenance, however, their exact 3D structures are still unknown.
ZHANG Jiayu, NIE Wenbo, TU Zhao, TU Zhao, WANG Yan, YANG Chunsheng   +5 more
doaj   +1 more source

Applications of Chemical Shift Imaging to Marine Sciences

Marine Drugs, 2010
The successful applications of magnetic resonance imaging (MRI) in medicine are mostly due to the non-invasive and non-destructive nature of MRI techniques.
Haakil Lee, Andrey Tikunov, Jeffrey M. Macdonald, Michael K. Stoskopf   +3 more
doaj   +1 more source

Gate-controlled spin polarized current in ferromagnetic single electron transistors

, 2001
We theoretically investigate spin dependent transport in ferromagnetic/normal metal/ferromagnetic single electron transistors by applying master equation calculations using a two dimensional space of states involving spin and charge degrees of freedom ...
A. Brataas, A. Brataas, A.N. Korotkov, C. D. Chen, C.D. Chen, D.V. Averin, H. Imamura, J. Barnaś, J. Barnaś, J. Barnaś, J. Barnaś, K. Majumdar, K. Ono, M. Johnson, M. Johnson, R. Meservey, S. Takahashi, Watson Kuo, X.H. Wang   +18 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Use of two-point and six-point Dixon MRI for fat fraction analysis in the lumbar vertebral bodies and paraspinal muscles in healthy dogs: comparison with magnetic resonance spectroscopy

Frontiers in Veterinary Science
IntroductionFatty degeneration of the vertebral bodies and paravertebral muscles is associated with the presence, severity, and prognosis of spinal disease such as intervertebral disc degeneration. Therefore, the fat fraction (FF) of the vertebral bodies
Hye-Won Lee, Ji-Yun Lee, Joo-Young Lee, Seung-Man Yu, Kija Lee, Sang-Kwon Lee   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Role of quantitative chemical shift magnetic resonance imaging and chemical shift subtraction technique in discriminating adenomatous from non adenomatous adrenal solid lesions

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Purpose: To evaluate role of quantitative assessment of chemical shift MR imaging and chemical shift subtraction technique in differentiating adenomatous from non-adenomatous adrenal lesions with comparison of accuracy level of each technique.
Ahmed H. Afifi, Hany L. Abdel Shafy, Adel A. Ramadan, Mohamed A. Ataa, Samir N. Assad   +4 more
doaj   +1 more source

Doping-induced band shifts and Lifshitz transitions in heavy-fermion metals

, 2012
For some heavy-fermion compounds, it has been suggested that a Fermi-surface-changing Lifshitz transition, which can be driven, e.g., by varying an applied magnetic field, occurs inside the heavy- fermion regime.
Benlagra, Adel, Vojta, Matthias
core   +1 more source