Results 41 to 50 of about 1,635,553 (300)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Chinese Journal of Magnetic Resonance, 2020 Cementitious materials have complex compositions and structures. Characterization of the hydration processes, and compositions and structure of productions of cementitious materials is challenging.
WANG Ke +3 more
doaj +1 more source
Carbon-13 n.m.r. investigation on the nitrogen methylation of the mono- and diazanaphthalenes [PDF]
, 1977 The 13C n.m.r. spectra of the N-methylated mono- and diazanaphthalenes have been recorded and analysed. It has been shown that N-methylation as well as N-protonation in cinnoline occur predominantly at the -nitrogen atom.
Ham, Dirk M.W. van den +2 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Mechanism of the fluxional behaviour in (1–5-η-cycloheptadienyl)-(1–5-η-cycloheptatrienyl)iron [PDF]
, 1977 Evidence for a 1.2-shift mechanism of the 1-5-η-cycloheptatrienyl moiety with respect to the central iron atom of the title compound is presented together with absolute assignments of the ^(13)C n.m.r. chemical shifts of the C_(7)H_(7) ring.
Blackborow, J. Richard +5 more
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Can MRI chemical shift imaging replace thymic biopsy in myasthenia gravis patients?
The Egyptian Journal of Radiology and Nuclear Medicine, 2022 Background Myasthenia gravis is a neuromuscular junction autoimmune condition characterized by muscle weakness. Many people with myasthenia gravis have thymic abnormalities, such as thymic lymphoid hyperplasia and thymic tumors, therefore, the thymus ...
Takeya Ahmed Taymour +3 more
doaj +1 more source
Magnetic shift of the chemical freezeout and electric charge fluctuations
, 2016 We discuss the effect of a strong magnetic field on the chemical freezeout points in the ultrarelativistic heavy-ion collision. As a result of the inverse magnetic catalysis or the magnetic inhibition, the crossover onset to hot and dense matter out of ...
Fukushima, Kenji, Hidaka, Yoshimasa
core +1 more source