Results 141 to 150 of about 8,888,554 (384)

Active catalyst construction for CO2 recycling via catalytic synthesis of N-doped carbon on supported Cu

Nature Communications, 2019
Bridging homogeneous and heterogeneous catalysis is a long-term pursuit in the field of catalysis. Here, the authors present results on integration of nano- and molecular catalysis via catalytic synthesis of nitrogen doped carbon layers on AlOx supported
Yajuan Wu, Tao Wang, Hongli Wang, Xinzhi Wang, Xingchao Dai, Feng Shi   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Iridium porphyrin-catalysed asymmetric carbene insertion into primary N-adjacent C–H bonds with TON over 1000000

Nature Communications
Selective functionalization of ubiquitous C-H bonds in organic molecules provides a straightforward and efficient approach to construct complex molecules with fewer synthetic steps and high atom economy, thus promoting more sustainable and economical ...
Zong-Rui Li, Kun Zhan, Yi-Jie Wang, Liang-Liang Wu, Guo-Lin Lu, Hao-Yang Wang, Xiao-Long Wan, Zhen-Jiang Xu, Kam-Hung Low, Chi-Ming Che   +9 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Sustainable recycling of polyamides via C–N bond cleavage facilitated by methyl tosylate under mild conditions

Nature Communications
The escalating issue of plastic “white pollution” urgently calls for efficient and sustainable recycling strategies. Herein, we propose an approach for the depolymerization of polyamides via alcoholysis, utilizing methyl tosylate as an activator to ...
Jitong Yang, Yifan Wang, Yifan Fan, Bing Xu, Tao Tu   +4 more
doaj   +1 more source

Abundances and search for vertical stratification in the atmospheres of four HgMn stars

, 2010
Using high resolution, high-S/N archival UVES spectra, we have performed a detailed spectroscopic analysis of 4 chemically peculiar HgMn stars (HD 71066, HD 175640, HD 178065 and HD 221507). Using spectrum synthesis, mean photospheric chemical abundances
Abt, Adelman, Adelman, Alecian, Aller, Babel, Balona, Castelli, Cowley, Dolk, Dubaj, F. LeBlanc, G. A. Wade, Gerbaldi, Grevesse, Hauschildt, Heacox, Holt, Hubrig, Hubrig, Hubrig, Hui-Bon-Hoa, Jomaron, Khalack, Khalack, Khan, Kochukhov, Kupka, Kurucz, Kurucz, Landstreet, Landstreet, Landstreet, Lanz, M. Thiam, Martin, Martin, Mathys, Michaud, Pickering, Preston, Ryabchikova, Ryabchikova, Ryabchikova, Ryabchikova, Savanov, Schaller, Shorlin, Sigut, Sigut, Smith, Smith, Smith, Smith, Takada-Hidai, V. Khalack, Wade, Wade, Wade, Wahlgren, White   +60 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Visible-light-mediated flow protocol for Achmatowicz rearrangement

Beilstein Journal of Organic Chemistry
The batch processes of APIs/pharmaceutical synthesis are prone to suffer significant limitations, including longer process time, shortage of skilled manpower, laborious post-synthetic work-up, etc.
Joachyutharayalu Oja, Sanjeev Kumar, Srihari Pabbaraja   +2 more
doaj   +1 more source

Design, synthesis and Chemical-physical characterization of photocatalytic inorganic nanocrystals for technological applications [PDF]

, 2013
Marco Marchetti
openalex   +1 more source