Results 251 to 260 of about 958,825 (298)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Chemical Synthesis and Antigenic Evaluation of Oligosaccharides of <i>Bordetella hinzii</i> O-Antigen Containing Unique Amidated 2,3-Diacetamido-2,3-dideoxy-alduronic Acids. [PDF]

JACS Au
Zhang L, Zheng Z, Zhang Y, Wu X, Tu Y, Liu C, Wang Z, Wang L, Yang Y, Zhang Q.   +9 more
europepmc   +1 more source

Enhancing chemical synthesis research with NLP: Word embeddings for chemical reagent identification-A case study on nano-FeCu. [PDF]

iScience
Cao D, Chan MK.
europepmc   +1 more source

Development of hydrophobic tag purifying monophosphorylated RNA for chemical synthesis of capped mRNA and enzymatic synthesis of circular mRNA. [PDF]

Nucleic Acids Res
Ototake M, Inagaki M, Kimura S, Onda K, Tada M, Kawaguchi D, Murase H, Fukuchi K, Gao Y, Kokubo K, Acharyya S, Meng Z, Ishida T, Kawasaki T, Abe N, Hashiya F, Kimura Y, Abe H.   +17 more
europepmc   +1 more source

Chemical Synthesis of 6-Azido-6-Deoxy Derivatives of Phosphatidylinositol Containing Different Fatty Acid Chains. [PDF]

Molecules
Molla MR, Gupta P, Rohokale R, Guo Z.
europepmc   +1 more source

Recent advances in the application of [2 + 2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products. [PDF]

Nat Prod Bioprospect
Hou SY, Yan BC, Sun HD, Puno PT.
europepmc   +1 more source

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Chemical synthesis of polysaccharides

Current Opinion in Chemical Biology, 2022
Here we summarize the chemical syntheses of glycans containing over 20 monosaccharide units, with the recent syntheses of ultra-long glycans, including a 92mer arabinogalactan, a 100mer and a 151mer mannan, and a 128mer rhamnomannan, being highlighted. The assembly strategies, glycosylation methods, and protecting group manipulations, which are crucial
Shengyang, Wang, You, Yang, Qian, Zhu, Guo-Qiang, Lin, Biao, Yu   +4 more
openaire   +2 more sources