Results 291 to 300 of about 8,888,554 (384)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Mutually Inspiring Biological and Chemical Synthesis of Fungal Bicyclo[2.2.2]diazaoctane Indole Alkaloids. [PDF]

Chem Rev
Du L, Dian L, Newmister SA, Xia Y, Luo G, Sherman DH, Li S.   +6 more
europepmc   +1 more source

Potassium-chemical synthesis of 3D graphene from CO₂and its excellent performance in HTM-free perovskite solar cells

, 2017
Wei Wei, Baoyun Hu, Fangming Jin, Zhenzi Jing, Yuexiang Li, Andrés A. García Blanco, Darı́o Stacchiola, Yun Hang Hu   +7 more
openalex   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Recent advances in chemical synthesis of phosphodiester linkages found in fungal mannans. [PDF]

Carbohydr Res
Ma Z, Ensley HE, Lowman DW, Kruppa MD, Williams DL.   +4 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Chemical Synthesis and Antifibrotic Properties of (±)-Cochlearol T, (±)-Ganocochlearin A, and (±)-Cochlearol Y. [PDF]

ACS Med Chem Lett
Kakde BN, An SW, Jebaraj YS, Neelam S, Wolf MTF, Tambar UK.   +5 more
europepmc   +1 more source

SYNTHESIS OF CARBON NANOSTRUCTURES FROM METHANE BY PLASMA- CHEMICAL METHOD

, 2016
Yu.V. Brylkin, G. N. Zalogin, Arthur Krasilnikov, N.F. Rudin   +3 more
openalex   +1 more source

Corrigendum to “Low temperature chemical synthesis of Mg doped GaN nanoparticles for high efficiency flexible homojunction solar cells”. [Sol. Energy 303 (2026) 114134]

Motahher A. Qaeed, M.K.M. Ali, Asad A. Thahe, Omar F. Farhat, A. Mindil, A.I. Aljameel, Ammar AL‐Farga   +6 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source