Results 51 to 60 of about 8,888,554 (384)

Chemical synthesis rewriting of a bacterial genome to achieve design flexibility and biological functionality

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The fundamental biological functions of a living cell are stored within the DNA sequence of its genome. Classical genetic approaches dissect the functioning of biological systems by analyzing individual genes, yet uncovering the essential ...
Jonathan Venetz, Luca Del Medico, A. Wölfle, Philipp Schächle, Yves Bucher, Donat Appert, Flavia Tschan, C. E. Flores-Tinoco, Mariëlle J. F. M. van Kooten, Rym Guennoun, S. Deutsch, Matthias Christen, Beat Christen   +12 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

One-Step Synthesis of Self-Stratification Core-Shell Latex for Antimicrobial Coating

Molecules, 2023
Herein, we describe a one-step method for synthesizing cationic acrylate-based core-shell latex (CACS latex), which is used to prepare architectural coatings with excellent antimicrobial properties.
Guanzhou Zhen, Yuanchun Mu, Peichen Yuan, Yankun Li, Xiaoyu Li   +4 more
doaj   +1 more source

Valorisation of glycerol by new mechanochemical processes [PDF]

, 2019
The search for new applications of glycerol, as a chemical platform from which a broad spectrum of new valuable derivatives can be obtained, is ongoing. In the present communication, a new mechano-chemical reactor is used for the valorisation of glycerol,
Halloumi, Samy, Lacoste, François, Lair, Valentin, Maireles-Torres, Pedro, Malpartida-García, Irene, Thiel, Julien   +5 more
core  

Organic crystalline polymers: structural properties and way to synthesis under high pressure

, 2018
We consider different structures, which can be obtained by polymerization of aromatic organic molecules under high pressures. These 2D and 3D covalently bonded organic polymers and their functionalization can pave the way to production of energy storage ...
Brazhkin, V. V., Kondrin, M. V., Lebed, Y. B., Nikolaev, N. A., Shulga, Y. M.   +4 more
core   +1 more source

Asymmetric preparation of antifungal 1-(4 -chlorophenyl)-1-cyclopropyl methanol and 1-(4 -chlorophenyl)-2-phenylethanol. Study of the detoxification mechanism by Botrytis cinerea [PDF]

, 2011
Chiral alcohols are important as bioactive compounds or as precursors to such molecules. On the basis of the different antifungal properties of the enantiopure alcohol derivatives of 4-chlorophenyl cyclopropyl ketone and benzyl 4-chlorophenyl ketone ...
Aleu Casatejada, Josefina, Bustillo Pérez, Antonio, González Collado, Isidro, Hernández Galán, Rosario, Pinedo Rivilla, Cristina   +4 more
core   +2 more sources

Chemical Synthesis of Circular Proteins [PDF]

Journal of Biological Chemistry, 2012
Circular proteins, once thought to be rare, are now commonly found in plants. Their chemical synthesis, once thought to be difficult, is now readily achievable. The enabling methodology is largely due to the advances in entropic chemical ligation to overcome the entropy barrier in coupling the N- and C-terminal ends of large peptide segments for either
Tam, James P., Wong, Clarence T. T.
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Machine learning-guided synthesis of advanced inorganic materials

, 2019
Synthesis of advanced inorganic materials with minimum number of trials is of paramount importance towards the acceleration of inorganic materials development.
Chouhan, Tushar, Golani, Prafful, Guan, Cuntai, Liu, Zheng, Lu, Yuhao, Tang, Bijun, Wang, Han, Xu, Manzhang, Xu, Quan, Zhou, Jiadong   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source