Results 91 to 100 of about 15,527,582 (268)

Chemical Technology Division Annual Progress Report

open access: yes, 1960
Report documenting the ongoing research of the Oak Ridge National Laboratory's Chemical Technology Division.
Oak Ridge National Laboratory. Chemical Technology Division.
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Technology within nationalized enterprises : a study of the factors influencing its acquisition and development by the Venezuelan petroleum industry

open access: yes, 1983
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1983.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCEBibliography: leaves 327-337.by Julian Obdulio Villalba.Ph ...
Villalba, Julian O
core  

Jean Hellot. A pioneer of chemical technology

open access: yesRevista CENIC Ciencias Químicas, 2009
Jean Hellot (1685-1766) is considered one of the founders of the chemical, metallurgical, and textile industry in France and Europe. Although he published little, his impact was significant in the chemical revolution that took place in the nineteenth ...
Jaime Wisniak
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Automated fault diagnosis of chemical process plants using model-based reasoning

open access: yes, 1989
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1989.Science hard copy bound in 2 v.Includes bibliographical references (leaves 300-307).by Francis Eric Finch.Ph ...
Finch, Francis Eric
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Novel multiphase chemical reaction systems enabled by microfabrication technology

open access: yes, 2001
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2001.Includes bibliographical references (p. 237-251).Advances in MEMS (micro-electromechanical systems) have enabled some of the "Lab-on-a-Chip" technologies and ...
Losey, Matthew W
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

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