Results 101 to 110 of about 1,800,080 (307)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PROCESS CONTROL IN THE EDUCATION OF ORGANIC CHEMICAL TECHNOLOGY

open access: yes, 2018
Laboratory practices for demonstrating the importance of advanced process control methods in the organic chemical technologies have been elaborated. It required the development of a system tha tintegrates the advantages of a reaction calorimeter and a ...
Faigl, Ferenc; Department of Organic Chemical Technology, Budapest University of Technology and Economics   +2 more
core  

Jean Hellot. A pioneer of chemical technology

open access: yesRevista CENIC Ciencias Químicas, 2009
Jean Hellot (1685-1766) is considered one of the founders of the chemical, metallurgical, and textile industry in France and Europe. Although he published little, his impact was significant in the chemical revolution that took place in the nineteenth ...
Jaime Wisniak
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Chemical and Biological Microsystems - What Are the Advantages of Small Systems?

open access: yes, 2010
The 25th annual Ashton Cary Lecture was presented on April 14, 2010 from 4-5 pm in room G011 of the Molecular Science and Engineering Building on the Georgia Tech Campus.The Cary Lecture SeriesMicrofabrication techniques have fueled spectacular advances ...
Jensen, Klavs F.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Specialized technology suppliers, international spillovers and investment: evidence from the chemical industry. [PDF]

open access: yes
In this paper we study how the development of specialized upstream technology suppliers in leading countries improves technology access and lowers investment costs for downstream firms in follower countries.
Gambardella, Alfonso   +2 more
core  

Effect of chemical structure on rocket fuel impulse [PDF]

open access: yes, 1951
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1951.Includes bibliographical references (leaves 92-93).by S.T.
Demetriades, S. T
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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