AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Sustainable chemical science and engineering: celebrating the 130th anniversary of Tianjin University. [PDF]
Gong J, Yuan Y, Zhao N, Qiao SZ.
europepmc +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Special issue on "Emerging applications of ultrasound technology in colloids, polymers and interfaces". [PDF]
Siah Ying PT, Manickam S, Wei TK, Ali A.
europepmc +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Correction: Revealing the photocatalytic dissociation of water molecules on rutile TiO<sub>2</sub> surface <i>via</i> hybrid functional based linear response time-dependent density functional theory. [PDF]
Wang L, Liu X, Li Q, Yang J, Hu W.
europepmc +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Correction: Construction of a homologous series of metal nanoclusters and implications for structure-activity correlations. [PDF]
Li Q +5 more
europepmc +1 more source
CHEMICAL PROCESSING TECHNOLOGY QUARTERLY PROGRESS REPORT, JANUARY-MARCH 1963
J.R. ed. Bower
openalex +2 more sources
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source

