Results 211 to 220 of about 1,457,648 (311)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Correction to "Enantioselective Synthesis of 2,3-Disubstituted Azetidines via Copper-Catalyzed Boryl Allylation of Azetines". [PDF]

J Am Chem Soc
Zhu M, Sun J.
europepmc   +1 more source

Impact of Blanching Treatments on the Physico-chemical Attributes of Curry Leaves Dried Using Solar Tunnel Technology

AV Bhogesara, Dhruvkumar J. Faldu, Ankitkumar Barad, R. H. Sabalpara, M. J. Gojiya   +4 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Chemolysis of Bio-Based Polyurethane Foams with Different Biopolyol Contents: Recovery and Possibility of Rebiopolyols Reuse in Sustainable Polyurethane Systems. [PDF]

Materials (Basel)
Kurańska M, Malewska E, Bonder Ł, Kucała M, Zemła M.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Feeding Preferences of <i>Agrilus zanthoxylumi</i> (Coleoptera: Buprestidae) in Relation to Host Plant Volatiles. [PDF]

Insects
Qi Y, Meng J, Jiang N, Liu X, Wu Y, Bai Y, Zhao Y, Liu B, Yang J, Wang Y, Xie S.   +10 more
europepmc   +1 more source

Comparison of chemical and energy consumption of acetic acid using hig boiling solvent technology with respect to conventional technologies using low boiling solvents

, 1993
Gökhan Alptekin
openalex   +1 more source

The Development of Risk Index Algorithm Which is applied to Chemical Accident Behaviour Analysis/Damage Prediction Models and Environmental Risk Map Technology

, 2018
Ji-Hoon Seo, Yoon Jae Kim, Jong Ryeul Sohn   +2 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source