Results 221 to 230 of about 1,457,648 (311)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correction: Shape programming of liquid crystal elastomers by two-stage wavelength-selective photopolymerization.

Mater Horiz
Bruining T, Tomé DR, Liu D.
europepmc   +1 more source

Insights into the Mechanisms and Functional Effects of Insoluble Dietary Fiber Modification: A Review. [PDF]

Foods
Li J, Lang W, Han S, Wu X, Hao F, Zhou Y, Du R, Song C.   +7 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Intelligent delignification: leveraging explainable AI for ozone transport modeling and optimization. [PDF]

Sci Rep
Rizwan M, Khan MA, Khan S, Baig KS, Ali A, Abdulnabi MS, Khan M.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Correction to "Rapid Activation of 3D-Printed Carbon Electrodes by Atmospheric Air Plasma: Toward Electrochemical Drug Analysis". [PDF]

ACS Omega
Kováč M, Gregová K, Švorc Ĺ, Zažímal F, Homola T, Gemeiner P.   +5 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Editorial: Precise chemical application technology for horticultural crops

Frontiers in Plant Science
Xue Li, Xue Li, Xiaolan Lv, Xiaolan Lv, Andreas Herbst, Jianli Song, Tao Xu, Tao Xu, Yannan Qi, Yannan Qi   +9 more
doaj   +1 more source