Results 41 to 50 of about 1,463,615 (338)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Rxn Hypergraph: a Hypergraph Attention Model for Chemical Reaction Representation [PDF]

arXiv, 2022
It is fundamental for science and technology to be able to predict chemical reactions and their properties. To achieve such skills, it is important to develop good representations of chemical reactions, or good deep learning architectures that can learn such representations automatically from the data. There is currently no universal and widely adopted
arxiv  

Nanomaterials for Chemical Sensing Technologies [PDF]

Journal of Sensors, 2009
1Department of Physical Technologies and New Materials, ENEA, Italian National Agency for New Technologies, Energy, and Sustainable Economic Development, Brindisi Research Center, 72100 Brindisi, Italy 2Department of Chemistry and Physics for Engineering and Materials, University of Brescia, 25133 Brescia, Italy 3 School of Electrical and Computer ...
Giorgio Sberveglieri, Yongxiang Li, Wojtek Wlodarski, Michele Penza   +3 more
openaire   +2 more sources

Research on the Innovative Ability of Green Chemical Technology in Eastern Region of China - Based on the perspective of Talent Competitiveness

Chemical Engineering Transactions, 2017
The chemical industry is the basic sector of the national economy. The status of chemical technology is directly related to the level of economic and social development in a country or region.
Yanyan Chen
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

FEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Enabling Technologies for the Future of Chemical Synthesis [PDF]

ACS Central Science, 2016
Technology is evolving at breakneck pace, changing the way we communicate, travel, find out information, and live our lives. Yet chemistry as a science has been slower to adapt to this rapidly shifting world. In this Outlook we use highlights from recent literature reports to describe how progresses in enabling technologies are altering this trend ...
Fitzpatrick, Daniel E, Battilocchio, Claudio, Ley, Steven V   +2 more
openaire   +4 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Analysis on application status of CCUS technology in emission reduction of modern coal chemical project in chemical industry [PDF]

E3S Web of Conferences
To gain a deeper understanding of the current application status of carbon capture, utilization, and storage (CCUS) technology in modern coal chemical projects aimed at reducing emissions in the chemical industry, a study on the application of CCUS ...
Zhan Yu
doaj   +1 more source