Results 51 to 60 of about 15,527,582 (268)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Center for Chemical Sensors and Chemical Information Technology (CCS): Molecular Recognition and Chemical Sensor Development at CCS

open access: yesCHIMIA, 2003
The Center for Chemical Sensors and Chemical Information Technology (CCS) at ETH-Zürich has devoted its activities to the development of highly selective devices that access chemical information about the composition of a specimen.
Ursula E. Spichiger-Keller
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Synthesis of operating procedures for complete chemical plants

open access: yes, 1990
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1990.Includes bibliographical references (leaves 192-195).by Ramachandran Lakshmanan.Ph ...
Lakshmanan, Ramachandran
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Key Factors Involved in Lamb Quality from Farm to Fork in Europe

open access: yesJournal of Integrative Agriculture, 2013
World lamb consumption is approximately 2 kg per capita with large variations between continents, e.g., 17 kg in Oceania vs. 0.7 kg in North America.
Carlos Sañudo   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Structure-property engineering and device fabrication of conjugated polymers by chemical vapor deposition

open access: yes, 2018
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2018Cataloged from PDF version of thesis. Page 223 blank.Includes bibliographical references.This thesis focuses on the in-situ molecular engineering of chemical ...
Wang, Xiaoxue,Ph. D.Massachusetts Institute of Technology.
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Bringing Together Academic and Industrial Chemistry: Edmund Ronalds’ Contribution

open access: yesSubstantia, 2019
Born 200 years ago, Edmund Ronalds (1819–1889) obtained his doctorate in Germany under Liebig, became a professor at Queen’s College Galway and ran the little-studied but significant Bonnington Chemical Works in Edinburgh.
Beverley F. Ronalds
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Chemical and physical mechanisms of soot formation

open access: yes, 1989
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1989.Includes bibliographical references (leaves 155-164).by Julian Thomas McKinnon, Jr.Ph ...
McKinnon, Julian Thomas
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