Results 121 to 130 of about 6,195,681 (305)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Bay Area transportation : state of the system 2002

The Metropolitan Transportation Commission (MTC) and Caltrans District 4 have engaged in a collaborative effort to assemble key facts and performance indicators of interest to Bay Area commuters and other travelers.
California. Metropolitan Transportation Commission, California. Dept. of Transportation. District 4   +1 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Traffic flow prediction based on improved deep extreme learning machine

Scientific Reports
A new hybrid prediction model is proposed for short-term traffic flow, which is based on Deep Extreme Learning Machine improved by Sparrow Search Algorithm (SSA-DELM).
Xiujuan Tian, Shuaihu Wu, Xue Xing, Huanying Liu, Heyao Gao, Chun Chen   +5 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Developing an interdisciplinary certificate program in transportation planning, phase 2 : the eCertificate. [PDF]

UTCM 476090-00056This proposal extends the delivery of the recently developed graduate Certificate in TransportationPlanning to a wider audience through the establishment of an Executive Certificate Program by distance(eCertificate).
Texas Transportation Institute. University Transportation Center for Mobility, Dumbaugh, Eric, Ndubisi, Forster   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Preparing tomorrow\u2019s transportation workforce : a Midwest summit.

Preparing Tomorrow\u2019s Transportation Workforce: A Midwest Summit, held April 27\u201328, 2010, in Ames, Iowa, was one of severalregional transportation workforce development summits held across the United States in 2009 and 2010 as part of a ...
Midwest Transportation Consortium, Albrecht, Christopher, Hallmark, Shauna, Iowa State University. Institute for Transportation, Nambisan, Shashi   +4 more
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Integrating the transportation system with a university transportation master plan. [PDF]

Introduction and Research Objectives-TxDOT commissioned TTI and the University of Texas at El Paso (UTEP) to perform aresearch study of the integration of the transportation system with the UTEPtransportation master plan-The objective is to document a ...
Aldret-Sanchez, Rafael, Shelton, Jeffrey Adam, Texas Transportation Institute   +2 more
core